Topic: skills
17,247 skills in this topic.
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bio-crispr-screens-library-design
CRISPR library design for genetic screens. Covers sgRNA selection, library composition, control design, and oligo ordering. Use when designing custom sgRNA libraries for knockout, activation, or interference screens.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-intervals-gtf-gff-handling
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-intervals-proximity-operations
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-duplicate-handling
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-alignment-io
Read, write, and convert multiple sequence alignment files using Biopython Bio.AlignIO. Supports Clustal, PHYLIP, Stockholm, FASTA, Nexus, and other alignment formats for phylogenetics and conservation analysis. Use when reading, writing, or converting alignment file formats.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-epidemiological-genomics-phylodynamics
Construct time-scaled phylogenies and infer evolutionary dynamics using TreeTime and BEAST2 for outbreak analysis. Estimate divergence times, molecular clock rates, and ancestral states. Use when dating outbreak origins, estimating transmission rates, or building time-calibrated trees.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-hi-c-analysis-matrix-operations
Balance, normalize, and transform Hi-C contact matrices using cooler and cooltools. Apply iterative correction (ICE), compute expected values, and generate observed/expected matrices. Use when normalizing or transforming Hi-C matrices.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-clinical-databases-clinvar-lookup
Query ClinVar for variant pathogenicity classifications, review status, and disease associations via REST API or local VCF. Use when determining clinical significance of variants for diagnostic or research purposes.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-imaging-mass-cytometry-spatial-analysis
Spatial analysis of cell neighborhoods and interactions in IMC data. Covers neighbor graphs, spatial statistics, and interaction testing. Use when analyzing spatial relationships between cell types, testing for neighborhood enrichment, or identifying cell-cell interaction patterns in imaging mass cytometry data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-de-results
Extract, filter, annotate, and export differential expression results from DESeq2 or edgeR. Use for identifying significant genes, applying multiple testing corrections, adding gene annotations, and preparing results for downstream analysis. Use when filtering and exporting DE analysis results.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-crispr-screens-mageck-analysis
MAGeCK (Model-based Analysis of Genome-wide CRISPR-Cas9 Knockout) for pooled CRISPR screen analysis. Covers count normalization, gene ranking, and pathway analysis. Use when identifying essential genes, drug targets, or resistance mechanisms from dropout or enrichment screens.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-batch-downloads
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-circos-plots
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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arxiv-search
Search arXiv physics, math, and computer science preprints using natural language queries. Powered by Valyu semantic search.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-de-edger-basics
Perform differential expression analysis using edgeR in R/Bioconductor. Use for analyzing RNA-seq count data with the quasi-likelihood F-test framework, creating DGEList objects, normalization, dispersion estimation, and statistical testing. Use when performing DE analysis with edgeR.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-assembly-scaffolding
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-interactive-visualization
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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benchling-integration
Benchling R&D platform integration. Access registry (DNA, proteins), inventory, ELN entries, workflows via API, build Benchling Apps, query Data Warehouse, for lab data management automation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-alignment-msa-statistics
Calculate alignment statistics including sequence identity, conservation scores, substitution matrices, and similarity metrics. Use when comparing alignment quality, measuring sequence divergence, and analyzing evolutionary patterns.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-expression-matrix-sparse-handling
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-chipseq-visualization
Visualize ChIP-seq data using deepTools, Gviz, and ChIPseeker. Create heatmaps, profile plots, and genome browser tracks. Visualize signal around peaks, TSS, or custom regions. Use when visualizing ChIP-seq signal and peaks.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-imaging-mass-cytometry-cell-segmentation
Cell segmentation from multiplexed tissue images. Covers deep learning (Cellpose, Mesmer) and classical approaches for nuclear and whole-cell segmentation. Use when extracting single-cell data from IMC or MIBI images after preprocessing.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-clinical-databases-pharmacogenomics
Query PharmGKB and CPIC for drug-gene interactions, pharmacogenomic annotations, and dosing guidelines. Use when predicting drug response from genetic variants or implementing clinical pharmacogenomics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-copy-number-cnv-visualization
Visualize copy number profiles, segments, and compare across samples. Create publication-quality plots of CNV data from CNVkit, GATK, or other callers. Use when creating genome-wide CNV plots, sample heatmaps, or chromosome-level visualizations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009