Topic: skills
17,247 skills in this topic.
-
bio-hi-c-analysis-matrix-operations
Balance, normalize, and transform Hi-C contact matrices using cooler and cooltools. Apply iterative correction (ICE), compute expected values, and generate observed/expected matrices. Use when normalizing or transforming Hi-C matrices.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-restriction-sites
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-single-cell-scatac-analysis
Single-cell ATAC-seq analysis with Signac (R/Seurat) and ArchR. Process 10X Genomics scATAC data, perform QC, dimensionality reduction, clustering, peak calling, and motif activity scoring with chromVAR. Use when analyzing single-cell ATAC-seq data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
benchling-integration
Benchling R&D platform integration. Access registry (DNA, proteins), inventory, ELN entries, workflows via API, build Benchling Apps, query Data Warehouse, for lab data management automation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-proteomics-differential-abundance
Statistical testing for differentially abundant proteins between conditions. Covers limma and MSstats workflows with multiple testing correction. Use when identifying proteins with significant abundance changes between experimental groups.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-clinical-databases-clinvar-lookup
Query ClinVar for variant pathogenicity classifications, review status, and disease associations via REST API or local VCF. Use when determining clinical significance of variants for diagnostic or research purposes.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-crispr-screens-library-design
CRISPR library design for genetic screens. Covers sgRNA selection, library composition, control design, and oligo ordering. Use when designing custom sgRNA libraries for knockout, activation, or interference screens.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-workflows-gwas-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-longread-medaka
Polish assemblies and call variants from Oxford Nanopore data using medaka. Uses neural networks trained on specific basecaller versions. Use when improving ONT-only assemblies or calling variants from Nanopore data without short-read polishing.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-variant-calling-deepvariant
Deep learning-based variant calling with Google DeepVariant. Provides high accuracy for germline SNPs and indels from Illumina, PacBio, and ONT data. Use when calling variants with DeepVariant deep learning caller.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-genome-intervals-proximity-operations
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
biologist-analyst
Analyzes living systems and biological phenomena through biological lens using evolution, molecular biology,
ecology, and systems biology frameworks.
Provides insights on mechanisms, adaptations, interactions, and life processes.
Use when: Biological systems, health issues, evolutionary questions, ecological problems, biotechnology.
Evaluates: Function, structure, heredity, evolution, interactions, molecular mechanisms.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-variant-normalization
Normalize indel representation and split multiallelic variants using bcftools norm. Use when comparing variants from different callers or preparing VCF for downstream analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-alignment-msa-statistics
Calculate alignment statistics including sequence identity, conservation scores, substitution matrices, and similarity metrics. Use when comparing alignment quality, measuring sequence divergence, and analyzing evolutionary patterns.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
chemist-analyst
Analyzes events through chemistry lens using molecular structure, reaction mechanisms, thermodynamics,
kinetics, and analytical techniques (spectroscopy, chromatography, mass spectrometry).
Provides insights on chemical processes, material properties, reaction pathways, synthesis, and analytical methods.
Use when: Chemical reactions, material analysis, synthesis planning, process optimization, environmental chemistry.
Evaluates: Molecular structure, reaction mechanisms, yield, selectivity, safety, environmental impact.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-sam-bam-basics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-long-read-sequencing-isoseq-analysis
Analyze PacBio Iso-Seq data for full-length isoform discovery and quantification. Use when characterizing transcript diversity or identifying novel splice variants.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-longread-qc
Quality control for long-read sequencing data using NanoPlot, NanoStat, and chopper. Generate QC reports, filter reads by length and quality, and visualize read characteristics. Use when assessing ONT or PacBio run quality or filtering reads before assembly or alignment.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-systems-biology-metabolic-reconstruction
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-liquid-biopsy-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-write-sequences
Write biological sequences to files (FASTA, FASTQ, GenBank, EMBL) using Biopython Bio.SeqIO. Use when saving sequences, creating new sequence files, or outputting modified records.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
chatehr-clinician-assistant
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
chip-clonal-hematopoiesis-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
-
bio-workflows-cnv-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009