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Topic: skills

17,247 skills in this topic.

open-targets-search Search Open Targets drug-disease associations with natural language queries. Target validation powered by Valyu semantic search.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-causal-genomics-fine-mapping Identify likely causal variants within GWAS loci using SuSiE for sum of single effects regression and FINEMAP for shotgun stochastic search. Computes posterior inclusion probabilities and credible sets to prioritize variants for functional follow-up. Use when narrowing GWAS association signals to candidate causal variants or building credible sets for functional validation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-clip-seq-clip-motif-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-alignment-msa-parsing Parse and analyze multiple sequence alignments using Biopython. Extract sequences, identify conserved regions, analyze gaps, work with annotations, and manipulate alignment data for downstream analysis. Use when parsing or manipulating multiple sequence alignments.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-restriction-fragment-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
equity-scorer Compute HEIM diversity and equity metrics from VCF or ancestry data. Generates heterozygosity, FST, PCA plots, and a composite HEIM Equity Score with markdown reports.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
epigenomics-methylgpt-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
epidemiologist-analyst Analyzes disease patterns and health events through epidemiological lens using surveillance systems, outbreak investigation methods, and disease modeling frameworks. Provides insights on disease spread, risk factors, prevention strategies, and public health interventions. Use when: Disease outbreaks, health policy evaluation, risk assessment, intervention planning. Evaluates: Transmission dynamics, risk factors, causality, population health impact, intervention effectiveness.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
scientific-slides Build slide decks and presentations for research talks. Use this for making PowerPoint slides, conference presentations, seminar talks, research presentations, thesis defense slides, or any scientific talk. Provides slide structure, design templates, timing guidance, and visual validation. Works with PowerPoint and LaTeX Beamer.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-chipseq-qc ChIP-seq quality control metrics including FRiP (Fraction of Reads in Peaks), cross-correlation analysis (NSC/RSC), library complexity, and IDR (Irreproducibility Discovery Rate) for replicate concordance. Use to assess experiment quality before downstream analysis. Use when assessing ChIP-seq data quality metrics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tooluniverse-metabolomics Comprehensive metabolomics research skill for identifying metabolites, analyzing studies, and searching metabolomics databases. Integrates HMDB (220k+ metabolites), MetaboLights, Metabolomics Workbench, and PubChem. Use when asked to identify or annotate metabolites (HMDB IDs, chemical properties, pathways), retrieve metabolomics study information from MetaboLights (MTBLS*) or Metabolomics Workbench (ST*), search for studies by keywords or disease, or generate comprehensive metabolomics research reports.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tiledbvcf Efficient storage and retrieval of genomic variant data using TileDB. Scalable VCF/BCF ingestion, incremental sample addition, compressed storage, parallel queries, and export capabilities for population genomics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
binding-characterization Guidance for SPR and BLI binding characterization experiments. Use when: (1) Planning binding kinetics experiments, (2) Troubleshooting poor/no binding signal, (3) Interpreting kinetic data artifacts, (4) Choosing between SPR vs BLI platforms.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-admet-prediction Predicts ADMET properties using ADMETlab 3.0 API or DeepChem models. Estimates bioavailability, CYP inhibition, hERG liability, and 119 toxicity endpoints with uncertainty quantification. Filters for PAINS and other structural alerts. Use when filtering compounds for drug-likeness or prioritizing leads by predicted safety.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
scikit-survival Comprehensive toolkit for survival analysis and time-to-event modeling in Python using scikit-survival. Use this skill when working with censored survival data, performing time-to-event analysis, fitting Cox models, Random Survival Forests, Gradient Boosting models, or Survival SVMs, evaluating survival predictions with concordance index or Brier score, handling competing risks, or implementing any survival analysis workflow with the scikit-survival library.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-flow-cytometry-doublet-detection Detect and remove doublets from flow and mass cytometry data. Covers FSC/SSC gating and computational doublet detection methods. Use when filtering out cell aggregates before clustering or quantitative analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
esm Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this skill when working with protein sequences, structures, or function prediction; designing novel proteins; generating protein embeddings; performing inverse folding; or conducting protein engineering tasks. Supports both local model usage and cloud-based Forge API for scalable inference.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tooluniverse-epigenomics Production-ready genomics and epigenomics data processing for BixBench questions. Handles methylation array analysis (CpG filtering, differential methylation, age-related CpG detection, chromosome-level density), ChIP-seq peak analysis (peak calling, motif enrichment, coverage stats), ATAC-seq chromatin accessibility, multi-omics integration (expression + methylation correlation), and genome-wide statistics. Pure Python computation (pandas, scipy, numpy, pysam, statsmodels) plus ToolUniverse annotation tools (Ensembl, ENCODE, SCREEN, JASPAR, ReMap, RegulomeDB, ChIPAtlas). Supports BED, BigWig, methylation beta-value matrices, Illumina manifest files, and multi-sample clinical data. Use when processing methylation data, ChIP-seq peaks, ATAC-seq signals, or answering questions about CpG sites, differential methylation, chromatin accessibility, histone marks, or epigenomic statistics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
using-superpowers Use when starting any conversation - establishes how to find and use skills, requiring Skill tool invocation before ANY response including clarifying questions
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
scvi-tools This skill should be used when working with single-cell omics data analysis using scvi-tools, including scRNA-seq, scATAC-seq, CITE-seq, spatial transcriptomics, and other single-cell modalities. Use this skill for probabilistic modeling, batch correction, dimensionality reduction, differential expression, cell type annotation, multimodal integration, and spatial analysis tasks.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
matchms Mass spectrometry analysis. Process mzML/MGF/MSP, spectral similarity (cosine, modified cosine), metadata harmonization, compound ID, for metabolomics and MS data processing.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-population-genetics-scikit-allel-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tooluniverse-phylogenetics Production-ready phylogenetics and sequence analysis skill for alignment processing, tree analysis, and evolutionary metrics. Computes treeness, RCV, treeness/RCV, parsimony informative sites, evolutionary rate, DVMC, tree length, alignment gap statistics, GC content, and bootstrap support using PhyKIT, Biopython, and DendroPy. Performs NJ/UPGMA/parsimony tree construction, Robinson-Foulds distance, Mann-Whitney U tests, and batch analysis across gene families. Integrates with ToolUniverse for sequence retrieval (NCBI, UniProt, Ensembl) and tree annotation. Use when processing FASTA/PHYLIP/Nexus/Newick files, computing phylogenetic metrics, comparing taxa groups, or answering questions about alignments, trees, parsimony, or molecular evolution.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflows-imc-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009