Topic: skills
17,247 skills in this topic.
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multimodal-radpath-fusion-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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vcf-manipulation
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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scientific-critical-thinking
Evaluate research rigor. Assess methodology, experimental design, statistical validity, biases, confounding, evidence quality (GRADE, Cochrane ROB), for critical analysis of scientific claims.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-clinical-databases-gnomad-frequencies
Query gnomAD for population allele frequencies to assess variant rarity. Use when filtering variants by population frequency for rare disease analysis or determining if a variant is common in the general population.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-spatial-data-io
Load spatial transcriptomics data from Visium, Xenium, MERFISH, Slide-seq, and other platforms using Squidpy and SpatialData. Read Space Ranger outputs, convert formats, and access spatial coordinates. Use when loading Visium, Xenium, MERFISH, or other spatial data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-genome-assembly-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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vcf-basics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-molecular-io
Reads, writes, and converts molecular file formats (SMILES, SDF, MOL2, PDB) using RDKit and Open Babel. Handles structure parsing, canonicalization, and full standardization pipeline including sanitization, normalization, and tautomer canonicalization. Use when loading chemical libraries, converting formats, or preparing molecules for analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-experimental-design-sample-size
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-multi-omics-integration
Integrate and analyze multiple omics datasets (transcriptomics, proteomics, epigenomics, genomics, metabolomics) for systems biology and precision medicine. Performs cross-omics correlation, multi-omics clustering (MOFA+, NMF), pathway-level integration, and sample matching. Coordinates ToolUniverse skills for expression data (RNA-seq), epigenomics (methylation, ChIP-seq), variants (SNVs, CNVs), protein interactions, and pathway enrichment. Use when analyzing multi-omics datasets, performing integrative analysis, discovering multi-omics biomarkers, studying disease mechanisms across molecular layers, or conducting systems biology research that requires coordinated analysis of transcriptome, genome, epigenome, proteome, and metabolome data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-crispr-screens-screen-qc
Quality control for pooled CRISPR screens. Covers library representation, read distribution, replicate correlation, and essential gene recovery. Use when assessing screen quality before hit calling or diagnosing poor screen performance.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-phylo-tree-io
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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deepchem
Molecular machine learning toolkit. Property prediction (ADMET, toxicity), GNNs (GCN, MPNN), MoleculeNet benchmarks, pretrained models, featurization, for drug discovery ML.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-reference-operations
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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clinvar-database
Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs, for genomic medicine.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-single-cell-cell-communication
Infer cell-cell communication networks from scRNA-seq data using CellChat, NicheNet, and LIANA for ligand-receptor interaction analysis. Use when inferring ligand-receptor interactions between cell types.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-epitranscriptomics-m6a-peak-calling
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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solublempnn
Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation.
For standard design, use proteinmpnn. For ligand-aware design, use ligandmpnn.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-atacseq-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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vcf-statistics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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scfoundation-model-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-methylation-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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chemcrow-drug-discovery
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-read-qc-contamination-screening
Detect sample contamination and cross-species reads using FastQ Screen. Screen reads against multiple reference genomes to identify bacterial, viral, adapter, or sample swap contamination. Use when suspecting cross-contamination or working with samples prone to microbial contamination.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009