Topic: skills
17,247 skills in this topic.
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bio-methylation-dmr-detection
Differentially methylated region (DMR) detection using methylKit tiles, bsseq BSmooth, and DMRcate. Use when identifying contiguous genomic regions with methylation differences between experimental conditions or cell types.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-microbiome-qiime2-workflow
QIIME2 command-line workflow for 16S/ITS amplicon analysis. Alternative to DADA2/phyloseq R workflow with built-in provenance tracking. Use when preferring CLI over R, needing reproducible provenance, or working within QIIME2 ecosystem.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-multipanel-figures
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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clinvar-database
Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs, for genomic medicine.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-sequence-statistics
Calculate sequence statistics (N50, length distribution, GC content, summary reports) using Biopython. Use when analyzing sequence datasets, generating QC reports, or comparing assemblies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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claw-semantic-sim
Semantic Similarity Index for disease research literature using PubMedBERT embeddings
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-rna-quantification-featurecounts-counting
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-single-cell-cell-communication
Infer cell-cell communication networks from scRNA-seq data using CellChat, NicheNet, and LIANA for ligand-receptor interaction analysis. Use when inferring ligand-receptor interactions between cell types.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-proteomics-data-import
Load and parse mass spectrometry data formats including mzML, mzXML, and quantification tool outputs like MaxQuant proteinGroups.txt. Use when starting a proteomics analysis with raw or processed MS data. Handles contaminant filtering and missing value assessment.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-single-cell-markers-annotation
Find marker genes and annotate cell types in single-cell RNA-seq using Seurat (R) and Scanpy (Python). Use for differential expression between clusters, identifying cluster-specific markers, scoring gene sets, and assigning cell type labels. Use when finding marker genes and annotating clusters.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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pdf-processing
Extract text and tables from PDF files, fill forms, merge documents. Use when working with PDF files or when the user mentions PDFs, forms, or document extraction.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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chematagent-drug-discovery
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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claw-metagenomics
Shotgun metagenomics profiling — taxonomy, resistome, and functional pathways
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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parameter-optimization
Explore and optimize simulation parameters via design of experiments (DOE), sensitivity analysis, and optimizer selection. Use for calibration, uncertainty studies, parameter sweeps, LHS sampling, Sobol analysis, surrogate modeling, or Bayesian optimization setup.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-phylo-tree-io
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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data-visualization-expert
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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polars
Fast in-memory DataFrame library for datasets that fit in RAM. Use when pandas is too slow but data still fits in memory. Lazy evaluation, parallel execution, Apache Arrow backend. Best for 1-100GB datasets, ETL pipelines, faster pandas replacement. For larger-than-RAM data use dask or vaex.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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gtars
High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection, tokenization for ML models, or fragment analysis in computational genomics and machine learning applications.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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docx
Use this skill whenever the user wants to create, read, edit, or manipulate Word documents (.docx files). Triggers include: any mention of 'Word doc', 'word document', '.docx', or requests to produce professional documents with formatting like tables of contents, headings, page numbers, or letterheads. Also use when extracting or reorganizing content from .docx files, inserting or replacing images in documents, performing find-and-replace in Word files, working with tracked changes or comments, or converting content into a polished Word document. If the user asks for a 'report', 'memo', 'letter', 'template', or similar deliverable as a Word or .docx file, use this skill. Do NOT use for PDFs, spreadsheets, Google Docs, or general coding tasks unrelated to document generation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-de-visualization
Visualize differential expression results using DESeq2/edgeR built-in functions. Covers plotMA, plotDispEsts, plotCounts, plotBCV, sample distance heatmaps, and p-value histograms. Use when visualizing differential expression results.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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crisis-response-protocol
Handle mental health crisis situations in AI coaching safely. Use when implementing crisis detection, safety protocols, emergency escalation, or suicide prevention features. Activates for crisis keywords, safety planning, hotline integration, and risk assessment.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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jaspar-database
Query JASPAR for transcription factor binding site (TFBS) profiles (PWMs/PFMs). Search by TF name, species, or class; scan DNA sequences for TF binding sites; compare matrices; essential for regulatory genomics, motif analysis, and GWAS regulatory variant interpretation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-comparative-genomics-synteny-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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gwas-lookup
Federated variant lookup across 9 genomic databases — GWAS Catalog, Open Targets, PheWeb (UKB, FinnGen, BBJ), GTEx, eQTL Catalogue, and more.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009