Topic: skills
17,247 skills in this topic.
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bio-proteomics-data-import
Load and parse mass spectrometry data formats including mzML, mzXML, and quantification tool outputs like MaxQuant proteinGroups.txt. Use when starting a proteomics analysis with raw or processed MS data. Handles contaminant filtering and missing value assessment.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bone-marrow-ai-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-structural-biology-modern-structure-prediction
Predict protein structures using modern ML models including AlphaFold3, ESMFold, Chai-1, and Boltz-1. Use when predicting structures for novel proteins, protein complexes, or when comparing predictions across multiple methods.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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protein-qc
Quality control metrics and filtering thresholds for protein design. Use this skill when: (1) Evaluating design quality for binding, expression, or structure, (2) Setting filtering thresholds for pLDDT, ipTM, PAE, (3) Checking sequence liabilities (cysteines, deamidation, polybasic clusters), (4) Creating multi-stage filtering pipelines, (5) Computing PyRosetta interface metrics (dG, SC, dSASA), (6) Checking biophysical properties (instability, GRAVY, pI), (7) Ranking designs with composite scoring.
This skill provides research-backed thresholds from binder design competitions and published benchmarks.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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ena-database
Access European Nucleotide Archive via API/FTP. Retrieve DNA/RNA sequences, raw reads (FASTQ), genome assemblies by accession, for genomics and bioinformatics pipelines. Supports multiple formats.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-genome-assembly-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-tcr-bcr-analysis-scirpy-analysis
Analyze single-cell TCR and BCR data integrated with gene expression using scirpy. Use when working with 10x Genomics VDJ data alongside scRNA-seq or when integrating immune receptor information with cell state analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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varCADD
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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cryoem-ai-drug-design-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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pymoo
Multi-objective optimization framework. NSGA-II, NSGA-III, MOEA/D, Pareto fronts, constraint handling, benchmarks (ZDT, DTLZ), for engineering design and optimization problems.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-comparative-genomics-synteny-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-tcr-bcr-analysis-repertoire-visualization
Create publication-quality visualizations of immune repertoire data including circos plots, clone tracking, diversity plots, and network graphs. Use when generating figures for repertoire comparisons, clonal dynamics, or V(D)J gene usage.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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gatk-variant-calling
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-spatial-visualization
Visualize spatial transcriptomics data using Squidpy and Scanpy. Create tissue plots with gene expression, clusters, and annotations overlaid on histology images. Use when visualizing spatial expression patterns.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-read-qc-fastp-workflow
All-in-one read preprocessing with fastp including adapter trimming, quality filtering, deduplication, base correction, and HTML report generation. Use when preprocessing Illumina data and wanting a single fast tool instead of separate Cutadapt, Trimmomatic, and FastQC steps.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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ukb-navigator
Semantic search across UK Biobank's 12,000+ data fields and publications — find the right variables for your research question.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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scientific-critical-thinking
Evaluate research rigor. Assess methodology, experimental design, statistical validity, biases, confounding, evidence quality (GRADE, Cochrane ROB), for critical analysis of scientific claims.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-specialized-omics-plots
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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claw-ancestry-pca
Ancestry decomposition PCA against the Simons Genome Diversity Project
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-hi-c-analysis-compartment-analysis
Detect A/B compartments from Hi-C data using cooltools and eigenvector decomposition. Identify active (A) and inactive (B) chromatin compartments from contact matrices. Use when identifying A/B compartments from Hi-C data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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jaspar-database
Query JASPAR for transcription factor binding site (TFBS) profiles (PWMs/PFMs). Search by TF name, species, or class; scan DNA sequences for TF binding sites; compare matrices; essential for regulatory genomics, motif analysis, and GWAS regulatory variant interpretation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-methylation-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-molecular-io
Reads, writes, and converts molecular file formats (SMILES, SDF, MOL2, PDB) using RDKit and Open Babel. Handles structure parsing, canonicalization, and full standardization pipeline including sanitization, normalization, and tautomer canonicalization. Use when loading chemical libraries, converting formats, or preparing molecules for analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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data-visualization-expert
FreedomIntelligence/OpenClaw-Medical-Skills 2,009