Topic: skills
17,247 skills in this topic.
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jaspar-database
Query JASPAR for transcription factor binding site (TFBS) profiles (PWMs/PFMs). Search by TF name, species, or class; scan DNA sequences for TF binding sites; compare matrices; essential for regulatory genomics, motif analysis, and GWAS regulatory variant interpretation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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etetoolkit
Phylogenetic tree toolkit (ETE). Tree manipulation (Newick/NHX), evolutionary event detection, orthology/paralogy, NCBI taxonomy, visualization (PDF/SVG), for phylogenomics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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cellxgene-census
Query CZ CELLxGENE Census (61M+ cells). Filter by cell type/tissue/disease, retrieve expression data, integrate with scanpy/PyTorch, for population-scale single-cell analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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claw-semantic-sim
Semantic Similarity Index for disease research literature using PubMedBERT embeddings
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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literature-search
Comprehensive scientific literature search across PubMed, arXiv, bioRxiv, medRxiv. Natural language queries powered by Valyu semantic search.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-specialized-omics-plots
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bone-marrow-ai-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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cryoem-ai-drug-design-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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scientific-critical-thinking
Evaluate research rigor. Assess methodology, experimental design, statistical validity, biases, confounding, evidence quality (GRADE, Cochrane ROB), for critical analysis of scientific claims.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-read-qc-fastp-workflow
All-in-one read preprocessing with fastp including adapter trimming, quality filtering, deduplication, base correction, and HTML report generation. Use when preprocessing Illumina data and wanting a single fast tool instead of separate Cutadapt, Trimmomatic, and FastQC steps.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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varCADD
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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multimodal-radpath-fusion-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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protein-qc
Quality control metrics and filtering thresholds for protein design. Use this skill when: (1) Evaluating design quality for binding, expression, or structure, (2) Setting filtering thresholds for pLDDT, ipTM, PAE, (3) Checking sequence liabilities (cysteines, deamidation, polybasic clusters), (4) Creating multi-stage filtering pipelines, (5) Computing PyRosetta interface metrics (dG, SC, dSASA), (6) Checking biophysical properties (instability, GRAVY, pI), (7) Ranking designs with composite scoring.
This skill provides research-backed thresholds from binder design competitions and published benchmarks.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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wikipedia-search
Search and fetch structured content from Wikipedia using the MediaWiki API for reliable, encyclopedic information
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-structural-biology-modern-structure-prediction
Predict protein structures using modern ML models including AlphaFold3, ESMFold, Chai-1, and Boltz-1. Use when predicting structures for novel proteins, protein complexes, or when comparing predictions across multiple methods.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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joint-calling
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-spatial-visualization
Visualize spatial transcriptomics data using Squidpy and Scanpy. Create tissue plots with gene expression, clusters, and annotations overlaid on histology images. Use when visualizing spatial expression patterns.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-methylation-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-immunoinformatics-immunogenicity-scoring
Score and prioritize neoantigens and epitopes for immunogenicity using multi-factor models combining MHC binding, processing, expression, and sequence features. Rank candidates for vaccine design. Use when prioritizing epitopes for vaccine development or identifying the most immunogenic neoantigens.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-hi-c-analysis-compartment-analysis
Detect A/B compartments from Hi-C data using cooltools and eigenvector decomposition. Identify active (A) and inactive (B) chromatin compartments from contact matrices. Use when identifying A/B compartments from Hi-C data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-proteomics-data-import
Load and parse mass spectrometry data formats including mzML, mzXML, and quantification tool outputs like MaxQuant proteinGroups.txt. Use when starting a proteomics analysis with raw or processed MS data. Handles contaminant filtering and missing value assessment.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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claw-ancestry-pca
Ancestry decomposition PCA against the Simons Genome Diversity Project
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-molecular-io
Reads, writes, and converts molecular file formats (SMILES, SDF, MOL2, PDB) using RDKit and Open Babel. Handles structure parsing, canonicalization, and full standardization pipeline including sanitization, normalization, and tautomer canonicalization. Use when loading chemical libraries, converting formats, or preparing molecules for analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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pymoo
Multi-objective optimization framework. NSGA-II, NSGA-III, MOEA/D, Pareto fronts, constraint handling, benchmarks (ZDT, DTLZ), for engineering design and optimization problems.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009