Topic: skills
17,247 skills in this topic.
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bio-variant-calling-joint-calling
Joint genotype calling across multiple samples using GATK CombineGVCFs and GenotypeGVCFs. Essential for cohort studies, population genetics, and leveraging VQSR. Use when performing joint genotyping across multiple samples.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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numerical-integration
Select and configure time integration methods for ODE/PDE simulations. Use when choosing explicit/implicit schemes, setting error tolerances, adapting time steps, diagnosing integration accuracy, planning IMEX splitting, or handling stiff/non-stiff coupled systems.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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spatial-statistics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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clinicaltrials-database
Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research and patient matching.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-rnaseq-qc
RNA-seq specific quality control including rRNA contamination detection, strandedness verification, gene body coverage, and transcript integrity metrics. Use when validating RNA-seq libraries before differential expression analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-proteomics-peptide-identification
Peptide-spectrum matching and protein identification from MS/MS data. Use when identifying peptides from tandem mass spectra. Covers database searching, spectral library matching, and FDR estimation using target-decoy approaches.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-alignment-files-bam-statistics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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histolab
Digital pathology image processing toolkit for whole slide images (WSI). Use this skill when working with histopathology slides, processing H&E or IHC stained tissue images, extracting tiles from gigapixel pathology images, detecting tissue regions, segmenting tissue masks, or preparing datasets for computational pathology deep learning pipelines. Applies to WSI formats (SVS, TIFF, NDPI), tile-based analysis, and histological image preprocessing workflows.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-epidemiological-genomics-variant-surveillance
Assign pathogen lineages and track variants using Nextclade and pangolin for viral surveillance. Monitor variant prevalence and identify emerging variants of concern. Use when classifying viral sequences, tracking lineage dynamics, or monitoring for variants of concern.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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scikit-learn
Machine learning in Python with scikit-learn. Use when working with supervised learning (classification, regression), unsupervised learning (clustering, dimensionality reduction), model evaluation, hyperparameter tuning, preprocessing, or building ML pipelines. Provides comprehensive reference documentation for algorithms, preprocessing techniques, pipelines, and best practices.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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umap-learn
UMAP dimensionality reduction. Fast nonlinear manifold learning for 2D/3D visualization, clustering preprocessing (HDBSCAN), supervised/parametric UMAP, for high-dimensional data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-virtual-screening
Performs structure-based virtual screening using AutoDock Vina 1.2 for molecular docking. Prepares receptor PDBQT files, generates ligand conformers, defines binding site boxes, and ranks compounds by predicted binding affinity. Use when screening chemical libraries against a protein structure to find potential binders.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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spatial-deconvolution
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-reporting-figure-export
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-single-cell-doublet-detection
Detect and remove doublets (multiple cells captured in one droplet) from single-cell RNA-seq data. Uses Scrublet (Python), DoubletFinder (R), and scDblFinder (R). Essential QC step before clustering to avoid artificial cell populations. Use when identifying and removing doublets from scRNA-seq data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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microbiome-cancer-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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docx
Comprehensive document creation, editing, and analysis with support for tracked changes, comments, formatting preservation, and text extraction. When Claude needs to work with professional documents (.docx files) for: (1) Creating new documents, (2) Modifying or editing content, (3) Working with tracked changes, (4) Adding comments, or any other document tasks
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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mesh-generation
Plan and evaluate mesh generation for numerical simulations. Use when choosing grid resolution, checking aspect ratios/skewness, estimating mesh quality constraints, or planning adaptive mesh refinement for PDE discretization.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-read-qc-umi-processing
Extract, process, and deduplicate reads using Unique Molecular Identifiers (UMIs) with umi_tools. Use when library prep includes UMIs and accurate molecule counting is needed, such as in single-cell RNA-seq, low-input RNA-seq, or targeted sequencing to distinguish PCR from biological duplicates.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-research-tools-biomarker-signature-studio
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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drug-labels-search
Search FDA drug labels with natural language queries. Official drug information, indications, and safety data via Valyu.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-fastq-to-variants
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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time-resolved-cryoem-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-crispr-screens-batch-correction
Batch effect correction for CRISPR screens. Covers normalization across batches, technical replicate handling, and batch-aware analysis. Use when combining screens from multiple batches or correcting systematic technical variation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009