Topic: skills
17,247 skills in this topic.
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pdb
Fetch and analyze protein structures from RCSB PDB. Use this skill when: (1) Need to download a structure by PDB ID, (2) Search for similar structures, (3) Prepare target for binder design, (4) Extract specific chains or domains, (5) Get structure metadata.
For sequence lookup, use uniprot. For binder design workflow, use binder-design.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-reverse-complement
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-upset-plots
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-phasing-imputation-imputation-qc
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-atac-seq-motif-deviation
Analyze transcription factor motif accessibility variability using chromVAR. Use when identifying which TF motifs show variable accessibility across samples or conditions in ATAC-seq data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-atac-seq-nucleosome-positioning
Extract nucleosome positions from ATAC-seq data using NucleoATAC, ATACseqQC, and fragment analysis. Use when analyzing chromatin organization, identifying nucleosome-free regions at promoters, or characterizing nucleosome occupancy patterns from ATAC-seq fragment size distributions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-differential-splicing
Detects differential alternative splicing between conditions using rMATS-turbo (BAM-based) or SUPPA2 diffSplice (TPM-based). Reports events with FDR-corrected significance and delta PSI effect sizes. Use when comparing splicing patterns between treatment groups, tissues, or disease states.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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molfeat
Molecular featurization for ML (100+ featurizers). ECFP, MACCS, descriptors, pretrained models (ChemBERTa), convert SMILES to features, for QSAR and molecular ML.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tumor-mutational-burden-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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find-skills
Helps users discover and install agent skills when they ask questions like "how do I do X", "find a skill for X", "is there a skill that can...", or express interest in extending capabilities. This skill should be used when the user is looking for functionality that might exist as an installable skill.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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nk-cell-therapy-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tcr-repertoire-analysis-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-crispr-screen-analysis
Comprehensive CRISPR screen analysis for functional genomics. Analyze pooled or arrayed CRISPR screens (knockout, activation, interference) to identify essential genes, synthetic lethal interactions, and drug targets. Perform sgRNA count processing, gene-level scoring (MAGeCK, BAGEL), quality control, pathway enrichment, and drug target prioritization. Use for CRISPR screen analysis, gene essentiality studies, synthetic lethality detection, functional genomics, drug target validation, or identifying genetic vulnerabilities.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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ai-analyzer
AI驱动的综合健康分析系统，整合多维度健康数据、识别异常模式、预测健康风险、提供个性化建议。支持智能问答和AI健康报告生成。
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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data-viz-plots
Create publication-quality plots and visualizations using matplotlib and seaborn. Works with ANY LLM provider (GPT, Gemini, Claude, etc.).
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-engineering-prime-editing-design
Design pegRNAs for prime editing using PrimeDesign algorithms. Generate spacer, PBS, and RT template sequences for precise genomic modifications without double-strand breaks. Use when designing prime editing experiments for precise insertions, deletions, or point mutations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-pharmacovigilance
Analyze drug safety signals from FDA adverse event reports, label warnings, and pharmacogenomic data. Calculates disproportionality measures (PRR, ROR), identifies serious adverse events, assesses pharmacogenomic risk variants. Use when asked about drug safety, adverse events, post-market surveillance, or risk-benefit assessment.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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protein-design-workflow
End-to-end guidance for protein design pipelines. Use this skill when: (1) Starting a new protein design project, (2) Need step-by-step workflow guidance, (3) Understanding the full design pipeline, (4) Planning compute resources and timelines, (5) Integrating multiple design tools.
For tool selection, use binder-design. For QC thresholds, use protein-qc.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-alignment-pairwise
Perform pairwise sequence alignment using Biopython Bio.Align.PairwiseAligner. Use when comparing two sequences, finding optimal alignments, scoring similarity, and identifying local or global matches between DNA, RNA, or protein sequences.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-immunotherapy-response-prediction
Predict patient response to immune checkpoint inhibitors (ICIs) using multi-biomarker integration. Given a cancer type, somatic mutations, and optional biomarkers (TMB, PD-L1, MSI status), performs systematic analysis across 11 phases covering TMB classification, neoantigen burden estimation, MSI/MMR assessment, PD-L1 evaluation, immune microenvironment profiling, mutation-based resistance/sensitivity prediction, clinical evidence retrieval, and multi-biomarker score integration. Generates a quantitative ICI Response Score (0-100), response likelihood tier, specific ICI drug recommendations with evidence, resistance risk factors, and a monitoring plan. Use when oncologists ask about immunotherapy eligibility, checkpoint inhibitor selection, or biomarker-guided ICI treatment decisions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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clinical-trials-search
Search ClinicalTrials.gov with natural language queries. Find clinical trials, enrollment, and outcomes using Valyu semantic search.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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ontology-mapper
Map materials science terms, crystal structures, and sample descriptions to ontology classes and properties. Supports any ontology registered in ontology_registry.json. Use when translating natural-language material descriptions to ontology terms, annotating simulation inputs with ontology metadata, or mapping crystal parameters (space group, Bravais lattice, lattice constants) to standardized ontology representations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-primer-design-qpcr-primers
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-pathway-reactome
Reactome pathway enrichment using ReactomePA package. Use when analyzing gene lists against Reactome's curated peer-reviewed pathway database. Performs over-representation analysis and GSEA with visualization and pathway hierarchy exploration.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009