Topic: skills
17,247 skills in this topic.
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bio-primer-design-qpcr-primers
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-hi-c-analysis-contact-pairs
Process Hi-C read pairs using pairtools. Parse alignments, filter duplicates, classify pairs, and generate contact statistics from Hi-C sequencing data. Use when processing raw Hi-C read pairs.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-systems-biology-context-specific-models
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-metagenomics-visualization
Visualize metagenomic profiles using R (phyloseq, microbiome) and Python (matplotlib, seaborn). Create stacked bar plots, heatmaps, PCA plots, and diversity analyses. Use when creating publication-quality figures from MetaPhlAn, Bracken, or other taxonomic profiling output.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-alignment-pairwise
Perform pairwise sequence alignment using Biopython Bio.Align.PairwiseAligner. Use when comparing two sequences, finding optimal alignments, scoring similarity, and identifying local or global matches between DNA, RNA, or protein sequences.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-engineering-prime-editing-design
Design pegRNAs for prime editing using PrimeDesign algorithms. Generate spacer, PBS, and RT template sequences for precise genomic modifications without double-strand breaks. Use when designing prime editing experiments for precise insertions, deletions, or point mutations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-experimental-design-power-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-imaging-mass-cytometry-data-preprocessing
Load and preprocess imaging mass cytometry (IMC) and MIBI data. Covers MCD/TIFF handling, hot pixel removal, and image normalization. Use when starting IMC analysis from raw MCD files or preparing images for segmentation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-alignment-validation
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-gwas-drug-discovery
Transform GWAS signals into actionable drug targets and repurposing opportunities. Performs locus-to-gene mapping, target druggability assessment, existing drug identification, safety profile evaluation, and clinical trial matching. Use when discovering drug targets from GWAS data, finding drug repurposing opportunities from genetic associations, or translating GWAS findings into therapeutic leads.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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nk-cell-therapy-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-chipseq-super-enhancers
Identifies super-enhancers from H3K27ac ChIP-seq data using ROSE and related tools. Use when studying cell identity genes, cancer-associated regulatory elements, or master transcription factor binding regions that cluster into large enhancer domains.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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cancer-metabolism-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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ensembl-database
Query Ensembl genome database REST API for 250+ species. Gene lookups, sequence retrieval, variant analysis, comparative genomics, orthologs, VEP predictions, for genomic research.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-pathway-reactome
Reactome pathway enrichment using ReactomePA package. Use when analyzing gene lists against Reactome's curated peer-reviewed pathway database. Performs over-representation analysis and GSEA with visualization and pathway hierarchy exploration.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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protein-design-workflow
End-to-end guidance for protein design pipelines. Use this skill when: (1) Starting a new protein design project, (2) Need step-by-step workflow guidance, (3) Understanding the full design pipeline, (4) Planning compute resources and timelines, (5) Integrating multiple design tools.
For tool selection, use binder-design. For QC thresholds, use protein-qc.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-microbiome-amplicon-processing
Amplicon sequence variant (ASV) inference from 16S rRNA or ITS amplicon sequencing using DADA2. Covers quality filtering, error learning, denoising, and chimera removal. Use when processing demultiplexed amplicon FASTQ files to generate an ASV table for downstream analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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exosome-ev-analysis-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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ontology-validator
Validate material sample annotations and data structures against ontology constraints. Use when checking if CMSO annotations are correct, verifying that required properties are present, or validating that object property relationships have consistent domain and range. Catches unknown classes, unknown properties, domain mismatches, and missing required fields.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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single-cell-clustering-and-batch-correction-with-omicverse
Guide Claude through omicverse's single-cell clustering workflow, covering preprocessing, QC, multimethod clustering, topic modeling, cNMF, and cross-batch integration as demonstrated in t_cluster.ipynb and t_single_batch.ipynb.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-clinical-databases-somatic-signatures
Extract and analyze mutational signatures from somatic variants using SigProfiler or MutationalPatterns to characterize mutagenic processes. Use when identifying DNA damage mechanisms or etiology in cancer genomes.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-microbiome-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-pdb-structure-modification
Modify protein structures using Biopython Bio.PDB. Use when transforming coordinates, removing atoms or residues, adding new entities, modifying B-factors and occupancies, or building structures programmatically.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-assembly-metagenome-assembly
FreedomIntelligence/OpenClaw-Medical-Skills 2,009