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Topic: openclaw

3,425 skills in this topic.

bio-local-blast
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-longread-structural-variants Detect structural variants from long-read alignments using Sniffles, cuteSV, and SVIM. Use when detecting deletions, insertions, inversions, translocations, or complex rearrangements from ONT or PacBio data, especially those missed by short-read methods.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
clinical-trials-search Search ClinicalTrials.gov with natural language queries. Find clinical trials, enrollment, and outcomes using Valyu semantic search.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-pathway-reactome Reactome pathway enrichment using ReactomePA package. Use when analyzing gene lists against Reactome's curated peer-reviewed pathway database. Performs over-representation analysis and GSEA with visualization and pathway hierarchy exploration.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-single-cell-clustering Dimensionality reduction and clustering for single-cell RNA-seq using Seurat (R) and Scanpy (Python). Use for running PCA, computing neighbors, clustering with Leiden/Louvain algorithms, generating UMAP/tSNE embeddings, and visualizing clusters. Use when performing dimensionality reduction and clustering on single-cell data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-primer-design-primer-validation
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
datamol Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery: SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-flow-cytometry-differential-analysis Differential abundance and state analysis for cytometry data. Compare cell populations between conditions using statistical methods. Use when testing for significant changes in cell frequencies or marker expression between groups.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-hi-c-analysis-contact-pairs Process Hi-C read pairs using pairtools. Parse alignments, filter duplicates, classify pairs, and generate contact statistics from Hi-C sequencing data. Use when processing raw Hi-C read pairs.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-proteomics-protein-inference Protein grouping and inference from peptide identifications. Use when resolving protein ambiguity from shared peptides. Handles protein groups and protein-level FDR control using parsimony and probabilistic approaches.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-genome-engineering-prime-editing-design Design pegRNAs for prime editing using PrimeDesign algorithms. Generate spacer, PBS, and RT template sequences for precise genomic modifications without double-strand breaks. Use when designing prime editing experiments for precise insertions, deletions, or point mutations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-microbiome-amplicon-processing Amplicon sequence variant (ASV) inference from 16S rRNA or ITS amplicon sequencing using DADA2. Covers quality filtering, error learning, denoising, and chimera removal. Use when processing demultiplexed amplicon FASTQ files to generate an ASV table for downstream analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-data-visualization-color-palettes
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-pathway-go-enrichment Gene Ontology over-representation analysis using clusterProfiler enrichGO. Use when identifying biological functions enriched in a gene list from differential expression or other analyses. Supports all three ontologies (BP, MF, CC), multiple ID types, and customizable statistical thresholds.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-basecalling Convert raw Nanopore signal data (FAST5/POD5) to nucleotide sequences using Dorado basecaller. Covers model selection, GPU acceleration, modified base detection, and quality filtering. Use when processing raw Nanopore data before alignment. Guppy is deprecated; use Dorado for all new analyses.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
chemistry-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-pdb-structure-navigation Navigate protein structure hierarchy using Biopython Bio.PDB SMCRA model. Use when accessing models, chains, residues, and atoms, iterating over structure levels, or extracting sequences from PDB files.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-ribo-seq-ribosome-stalling Detect ribosome pausing and stalling sites from Ribo-seq data at codon resolution. Use when studying translational regulation, identifying pause sites, or analyzing codon-specific translation dynamics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflows-clip-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflows-microbiome-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
crisis-detection-intervention-ai Detect crisis signals in user content using NLP, mental health sentiment analysis, and safe intervention protocols. Implements suicide ideation detection, automated escalation, and crisis resource integration. Use for mental health apps, recovery platforms, support communities. Activate on "crisis detection", "suicide prevention", "mental health NLP", "intervention protocol". NOT for general sentiment analysis, medical diagnosis, or replacing professional help.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-primer-design-qpcr-primers
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-imaging-mass-cytometry-data-preprocessing Load and preprocess imaging mass cytometry (IMC) and MIBI data. Covers MCD/TIFF handling, hot pixel removal, and image normalization. Use when starting IMC analysis from raw MCD files or preparing images for segmentation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-reverse-complement
FreedomIntelligence/OpenClaw-Medical-Skills 2,009