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Topic: openclaw

3,425 skills in this topic.

bio-metabolomics-statistical-analysis Statistical analysis for metabolomics data. Covers univariate testing, multivariate methods (PCA, PLS-DA), and biomarker discovery. Use when identifying differentially abundant metabolites or building classification models.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-population-genetics-population-structure
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-proteomics-protein-inference Protein grouping and inference from peptide identifications. Use when resolving protein ambiguity from shared peptides. Handles protein groups and protein-level FDR control using parsimony and probabilistic approaches.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-genome-engineering-prime-editing-design Design pegRNAs for prime editing using PrimeDesign algorithms. Generate spacer, PBS, and RT template sequences for precise genomic modifications without double-strand breaks. Use when designing prime editing experiments for precise insertions, deletions, or point mutations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-pathway-reactome Reactome pathway enrichment using ReactomePA package. Use when analyzing gene lists against Reactome's curated peer-reviewed pathway database. Performs over-representation analysis and GSEA with visualization and pathway hierarchy exploration.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-hi-c-analysis-hic-visualization Visualize Hi-C contact matrices, TADs, loops, and genomic features using matplotlib, cooltools, and HiCExplorer. Create triangle plots, virtual 4C, and multi-track figures. Use when visualizing contact matrices or genomic features.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-pdb-structure-modification Modify protein structures using Biopython Bio.PDB. Use when transforming coordinates, removing atoms or residues, adding new entities, modifying B-factors and occupancies, or building structures programmatically.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-local-blast
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-pileup-generation
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-methylation-bismark-alignment Bisulfite sequencing read alignment using Bismark with bowtie2/hisat2. Handles genome preparation and produces BAM files with methylation information. Use when aligning WGBS, RRBS, or other bisulfite-converted sequencing reads to a reference genome.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-expression-matrix-counts-ingest
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-hi-c-analysis-contact-pairs Process Hi-C read pairs using pairtools. Parse alignments, filter duplicates, classify pairs, and generate contact statistics from Hi-C sequencing data. Use when processing raw Hi-C read pairs.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-atac-seq-motif-deviation Analyze transcription factor motif accessibility variability using chromVAR. Use when identifying which TF motifs show variable accessibility across samples or conditions in ATAC-seq data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-primer-design-qpcr-primers
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-genome-engineering-hdr-template-design Design homology-directed repair donor templates for CRISPR knock-ins using primer3-py. Create ssODN, dsDNA, or plasmid templates with optimized homology arms. Use when designing donor templates for precise insertions, tagging, or allele replacement.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-ribo-seq-ribosome-stalling Detect ribosome pausing and stalling sites from Ribo-seq data at codon resolution. Use when studying translational regulation, identifying pause sites, or analyzing codon-specific translation dynamics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-longread-structural-variants Detect structural variants from long-read alignments using Sniffles, cuteSV, and SVIM. Use when detecting deletions, insertions, inversions, translocations, or complex rearrangements from ONT or PacBio data, especially those missed by short-read methods.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-population-genetics-plink-basics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-microbiome-taxonomy-assignment Taxonomic classification of ASVs using reference databases like SILVA, GTDB, or UNITE. Covers naive Bayes classifiers (DADA2, IDTAXA) and exact matching approaches. Use when assigning taxonomy to ASVs after DADA2 amplicon processing.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-experimental-design-power-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-epitranscriptomics-modification-visualization
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-restriction-mapping
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-proteomics-ptm-analysis Post-translational modification analysis including phosphorylation, acetylation, and ubiquitination. Covers site localization, motif analysis, and quantitative PTM analysis. Use when analyzing phosphoproteomic data or other modification-enriched samples.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-single-cell-cell-annotation Automated cell type annotation using reference-based methods including CellTypist, scPred, SingleR, and Azimuth for consistent, reproducible cell labeling. Use when automatically annotating cell types using reference datasets.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009