Topic: claude-code
35,830 skills in this topic.
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bio-chipseq-peak-annotation
Annotate ChIP-seq peaks to genomic features and genes using ChIPseeker. Assign peaks to promoters, exons, introns, and intergenic regions. Find nearest genes and calculate distance to TSS. Generate annotation plots and statistics. Use when annotating ChIP-seq peaks to genomic features.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-format-conversion
Convert between sequence file formats (FASTA, FASTQ, GenBank, EMBL) using Biopython Bio.SeqIO. Use when changing file formats or preparing data for different tools.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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chematagent-drug-discovery
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-small-rna-seq-mirdeep2-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tcm-constitution-analyzer
分析中医体质数据、识别体质类型、评估体质特征,并提供个性化养生建议。支持与营养、运动、睡眠等健康数据的关联分析。
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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claw-metagenomics
Shotgun metagenomics profiling — taxonomy, resistome, and functional pathways
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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clinical-interpretation
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-rna-quantification-featurecounts-counting
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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repro-enforcer
Export any bioinformatics analysis as a reproducible bundle with Conda environment, Singularity container definition, and Nextflow pipeline.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-rna-quantification-tximport-workflow
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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binder-design
Guidance for choosing the right protein binder design tool. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types.
For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bindcraft
End-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using different design protocols (fast, default, slow), (4) Need joint backbone and sequence optimization, (5) Want high experimental success rate.
For backbone-only generation, use rfdiffusion. For QC thresholds, use protein-qc. For tool selection guidance, use binder-design.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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MAGE
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-chipseq-peak-calling
ChIP-seq peak calling using MACS3 (or MACS2). Call narrow peaks for transcription factors or broad peaks for histone modifications. Supports input control, fragment size modeling, and various output formats including narrowPeak and broadPeak BED files. Use when calling peaks from ChIP-seq alignments.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-causal-genomics-mediation-analysis
Decompose genetic effects into direct and indirect paths through mediating variables using the mediation R package. Tests whether gene expression, methylation, or other molecular phenotypes mediate the effect of genetic variants on disease. Use when testing whether a molecular phenotype mediates the genotype-to-phenotype relationship.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-alignment-filtering
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-atac-seq-footprinting
Detect transcription factor binding sites through footprinting analysis in ATAC-seq data using TOBIAS. Use when identifying TF occupancy patterns within accessible regions, as TF binding protects DNA from Tn5 cutting.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-volcano-customization
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-genome-browser-tracks
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-blast-searches
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-comparative-genomics-ortholog-inference
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bindingdb-database
Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50). Search by target (UniProt ID), compound (SMILES/name), or pathogen. Essential for drug discovery, lead optimization, polypharmacology analysis, and structure-activity relationship (SAR) studies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-atac-seq-atac-peak-calling
Call accessible chromatin regions from ATAC-seq data using MACS3 with ATAC-specific parameters. Use when identifying open chromatin regions from aligned ATAC-seq BAM files, different from ChIP-seq peak calling.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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aav-vector-design-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009