Topic: claude-code
35,830 skills in this topic.
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ena-database
Access European Nucleotide Archive via API/FTP. Retrieve DNA/RNA sequences, raw reads (FASTQ), genome assemblies by accession, for genomics and bioinformatics pipelines. Supports multiple formats.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-isoform-switching
Analyzes isoform switching events and functional consequences using IsoformSwitchAnalyzeR. Predicts protein domain changes, NMD sensitivity, ORF alterations, and coding potential shifts between conditions. Use when investigating how splicing changes affect protein function.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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claw-metagenomics
Shotgun metagenomics profiling — taxonomy, resistome, and functional pathways
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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anndata
This skill should be used when working with annotated data matrices in Python, particularly for single-cell genomics analysis, managing experimental measurements with metadata, or handling large-scale biological datasets. Use when tasks involve AnnData objects, h5ad files, single-cell RNA-seq data, or integration with scanpy/scverse tools.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-machine-learning-omics-classifiers
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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molecular-glue-discovery-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-genome-assembly-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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gwas-lookup
Federated variant lookup across 9 genomic databases — GWAS Catalog, Open Targets, PheWeb (UKB, FinnGen, BBJ), GTEx, eQTL Catalogue, and more.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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rehabilitation-analyzer
分析康复训练数据、识别康复模式、评估康复进展,并提供个性化康复建议
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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brenda-database
Access BRENDA enzyme database via SOAP API. Retrieve kinetic parameters (Km, kcat), reaction equations, organism data, and substrate-specific enzyme information for biochemical research and metabolic pathway analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-de-visualization
Visualize differential expression results using DESeq2/edgeR built-in functions. Covers plotMA, plotDispEsts, plotCounts, plotBCV, sample distance heatmaps, and p-value histograms. Use when visualizing differential expression results.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-rna-quantification-featurecounts-counting
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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repro-enforcer
Export any bioinformatics analysis as a reproducible bundle with Conda environment, Singularity container definition, and Nextflow pipeline.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-single-cell-markers-annotation
Find marker genes and annotate cell types in single-cell RNA-seq using Seurat (R) and Scanpy (Python). Use for differential expression between clusters, identifying cluster-specific markers, scoring gene sets, and assigning cell type labels. Use when finding marker genes and annotating clusters.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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clinpgx
Query the ClinPGx API for pharmacogenomic gene-drug data, clinical annotations, CPIC guidelines, and FDA drug labels
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-intervals-bed-file-basics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-read-alignment-bowtie2-alignment
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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scrna-qc
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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solublempnn
Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation.
For standard design, use proteinmpnn. For ligand-aware design, use ligandmpnn.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-comparative-genomics-synteny-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-variant-calling-structural-variant-calling
Call structural variants (SVs) from short-read sequencing using Manta, Delly, and LUMPY. Detects deletions, insertions, inversions, duplications, and translocations that are too large for standard SNV callers. Use when detecting structural variants from short-read data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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nutrition-analyzer
分析营养数据、识别营养模式、评估营养状况,并提供个性化营养建议。支持与运动、睡眠、慢性病数据的关联分析。
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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polars
Fast in-memory DataFrame library for datasets that fit in RAM. Use when pandas is too slow but data still fits in memory. Lazy evaluation, parallel execution, Apache Arrow backend. Best for 1-100GB datasets, ETL pipelines, faster pandas replacement. For larger-than-RAM data use dask or vaex.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-spatial-data-io
Load spatial transcriptomics data from Visium, Xenium, MERFISH, Slide-seq, and other platforms using Squidpy and SpatialData. Read Space Ranger outputs, convert formats, and access spatial coordinates. Use when loading Visium, Xenium, MERFISH, or other spatial data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009