Topic: claude-code
35,830 skills in this topic.
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bio-workflows-multiome-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-clinical-databases-gnomad-frequencies
Query gnomAD for population allele frequencies to assess variant rarity. Use when filtering variants by population frequency for rare disease analysis or determining if a variant is common in the general population.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-chipseq-peak-annotation
Annotate ChIP-seq peaks to genomic features and genes using ChIPseeker. Assign peaks to promoters, exons, introns, and intergenic regions. Find nearest genes and calculate distance to TSS. Generate annotation plots and statistics. Use when annotating ChIP-seq peaks to genomic features.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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anndata
This skill should be used when working with annotated data matrices in Python, particularly for single-cell genomics analysis, managing experimental measurements with metadata, or handling large-scale biological datasets. Use when tasks involve AnnData objects, h5ad files, single-cell RNA-seq data, or integration with scanpy/scverse tools.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-ctdna-mutation-detection
Detects somatic mutations in circulating tumor DNA using variant callers optimized for low allele fractions with UMI-based error suppression. Reliably detects mutations at VAF above 0.5 percent using consensus-based approaches. Use when identifying tumor mutations from plasma DNA or tracking specific variants.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-spatial-visualization
Visualize spatial transcriptomics data using Squidpy and Scanpy. Create tissue plots with gene expression, clusters, and annotations overlaid on histology images. Use when visualizing spatial expression patterns.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-batch-processing
Process multiple sequence files in batch using Biopython. Use when working with many files, merging/splitting sequences, or automating file operations across directories.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-microbiome-qiime2-workflow
QIIME2 command-line workflow for 16S/ITS amplicon analysis. Alternative to DADA2/phyloseq R workflow with built-in provenance tracking. Use when preferring CLI over R, needing reproducible provenance, or working within QIIME2 ecosystem.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-methylation-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-single-cell-markers-annotation
Find marker genes and annotate cell types in single-cell RNA-seq using Seurat (R) and Scanpy (Python). Use for differential expression between clusters, identifying cluster-specific markers, scoring gene sets, and assigning cell type labels. Use when finding marker genes and annotating clusters.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-specialized-omics-plots
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-sequence-statistics
Calculate sequence statistics (N50, length distribution, GC content, summary reports) using Biopython. Use when analyzing sequence datasets, generating QC reports, or comparing assemblies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-single-cell-cell-communication
Infer cell-cell communication networks from scRNA-seq data using CellChat, NicheNet, and LIANA for ligand-receptor interaction analysis. Use when inferring ligand-receptor interactions between cell types.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-reference-operations
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-small-rna-seq-mirdeep2-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-variant-calling-structural-variant-calling
Call structural variants (SVs) from short-read sequencing using Manta, Delly, and LUMPY. Detects deletions, insertions, inversions, duplications, and translocations that are too large for standard SNV callers. Use when detecting structural variants from short-read data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-read-qc-fastp-workflow
All-in-one read preprocessing with fastp including adapter trimming, quality filtering, deduplication, base correction, and HTML report generation. Use when preprocessing Illumina data and wanting a single fast tool instead of separate Cutadapt, Trimmomatic, and FastQC steps.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-rna-quantification-featurecounts-counting
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-multipanel-figures
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-reporting-rmarkdown-reports
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-structural-biology-modern-structure-prediction
Predict protein structures using modern ML models including AlphaFold3, ESMFold, Chai-1, and Boltz-1. Use when predicting structures for novel proteins, protein complexes, or when comparing predictions across multiple methods.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-molecular-io
Reads, writes, and converts molecular file formats (SMILES, SDF, MOL2, PDB) using RDKit and Open Babel. Handles structure parsing, canonicalization, and full standardization pipeline including sanitization, normalization, and tautomer canonicalization. Use when loading chemical libraries, converting formats, or preparing molecules for analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-pathway-gsea
Gene Set Enrichment Analysis using clusterProfiler gseGO and gseKEGG. Use when analyzing ranked gene lists to find coordinated expression changes in gene sets without arbitrary significance cutoffs. Detects subtle but coordinated expression changes.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-genome-assembly-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009