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Topic: awesome

1,258 skills in this topic.

tooluniverse-gwas-snp-interpretation Interpret genetic variants (SNPs) from GWAS studies by aggregating evidence from multiple databases (GWAS Catalog, Open Targets Genetics, ClinVar). Retrieves variant annotations, GWAS trait associations, fine-mapping evidence, locus-to-gene predictions, and clinical significance. Use when asked to interpret a SNP by rsID, find disease associations for a variant, assess clinical significance, or answer questions like "What diseases is rs429358 associated with?" or "Interpret rs7903146".
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-metabolomics-targeted-analysis Targeted metabolomics analysis using MRM/SRM with standard curves. Covers absolute quantification, method validation, and quality assessment. Use when quantifying specific metabolites using calibration curves and internal standards.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-single-cell-perturb-seq Analyze Perturb-seq and CROP-seq CRISPR screening data integrated with scRNA-seq. Use when identifying gene function through pooled genetic perturbations in single cells.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tcga-bulk-data-preprocessing-with-omicverse Guide Claude through ingesting TCGA sample sheets, expression archives, and clinical carts into omicverse, initialising survival metadata, and exporting annotated AnnData files.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tooluniverse-target-research Gather comprehensive biological target intelligence from 9 parallel research paths covering protein info, structure, interactions, pathways, expression, variants, drug interactions, and literature. Features collision-aware searches, evidence grading (T1-T4), explicit Open Targets coverage, and mandatory completeness auditing. Use when users ask about drug targets, proteins, genes, or need target validation, druggability assessment, or comprehensive target profiling.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-pathway-wikipathways WikiPathways enrichment using clusterProfiler and rWikiPathways. Use when analyzing gene lists against community-curated open-source pathways. Performs over-representation analysis and GSEA for 30+ species.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
systematic-debugging Use when encountering any bug, test failure, or unexpected behavior, before proposing fixes
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-phasing-imputation-haplotype-phasing
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
subagent-driven-development Use when executing implementation plans with independent tasks in the current session
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-phasing-imputation-reference-panels
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
compbioagent-explorer
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-orchestrator Meta-agent that routes bioinformatics requests to specialised sub-skills. Handles file type detection, analysis planning, report generation, and reproducibility export.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflows-scrnaseq-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-multi-omics-mofa-integration Multi-Omics Factor Analysis (MOFA2) for unsupervised integration of multiple data modalities. Identifies shared and view-specific sources of variation. Use when integrating RNA-seq, proteomics, methylation, or other omics to discover latent factors driving biological variation across modalities.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-phylo-distance-calculations
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-phylo-modern-tree-inference
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-systems-biology-gene-essentiality
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-single-cell-trajectory-inference Infer developmental trajectories and pseudotime from single-cell RNA-seq data using Monocle3, Slingshot, and scVelo for RNA velocity analysis. Use when inferring developmental trajectories or pseudotime.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-phylo-tree-manipulation
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-single-cell-batch-integration Integrate multiple scRNA-seq samples/batches using Harmony, scVI, Seurat anchors, and fastMNN. Remove technical variation while preserving biological differences. Use when integrating multiple scRNA-seq batches or datasets.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-variant-calling-clinical-interpretation Clinical variant interpretation using ClinVar, ACMG guidelines, and pathogenicity predictors. Prioritize variants for diagnostic and research applications. Use when interpreting clinical significance of variants.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-microbiome-differential-abundance Differential abundance testing for microbiome data using compositionally-aware methods like ALDEx2, ANCOM-BC2, and MaAsLin2. Use when identifying taxa that differ between experimental groups while accounting for the compositional nature of microbiome data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tooluniverse-chemical-safety Comprehensive chemical safety and toxicology assessment integrating ADMET-AI predictions, CTD toxicogenomics, FDA label safety data, DrugBank safety profiles, and STITCH chemical-protein interactions. Performs predictive toxicology (AMES, DILI, LD50, carcinogenicity), organ/system toxicity profiling, chemical-gene-disease relationship mapping, regulatory safety extraction, and environmental hazard assessment. Use when asked about chemical toxicity, drug safety profiling, ADMET properties, environmental health risks, chemical hazard assessment, or toxicogenomic analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
clinical-reports Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), and patient documentation (SOAP, H&P, discharge summaries). Full support with templates, regulatory compliance (HIPAA, FDA, ICH-GCP), and validation tools.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009