Topic: openclaw
3,425 skills in this topic.
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tooluniverse-systems-biology
Comprehensive systems biology and pathway analysis using multiple pathway databases (Reactome, KEGG, WikiPathways, Pathway Commons, BioModels). Performs pathway enrichment, protein-pathway mapping, keyword searches, and systems-level analysis. Use when analyzing gene sets, exploring biological pathways, or investigating systems-level biology.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-crispr-screens-mageck-analysis
MAGeCK (Model-based Analysis of Genome-wide CRISPR-Cas9 Knockout) for pooled CRISPR screen analysis. Covers count normalization, gene ranking, and pathway analysis. Use when identifying essential genes, drug targets, or resistance mechanisms from dropout or enrichment screens.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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pubmed-database
Direct REST API access to PubMed. Advanced Boolean/MeSH queries, E-utilities API, batch processing, citation management. For Python workflows, prefer biopython (Bio.Entrez). Use this for direct HTTP/REST work or custom API implementations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-binder-discovery
Discover novel small molecule binders for protein targets using structure-based and ligand-based approaches. Creates actionable reports with candidate compounds, ADMET profiles, and synthesis feasibility. Use when users ask to find small molecules for a target, identify novel binders, perform virtual screening, or need hit-to-lead compound identification.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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geniml
This skill should be used when working with genomic interval data (BED files) for machine learning tasks. Use for training region embeddings (Region2Vec, BEDspace), single-cell ATAC-seq analysis (scEmbed), building consensus peaks (universes), or any ML-based analysis of genomic regions. Applies to BED file collections, scATAC-seq data, chromatin accessibility datasets, and region-based genomic feature learning.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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organoid-drug-response-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-expression-matrix-sparse-handling
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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vcf-annotator
Annotate VCF variants with VEP, ClinVar, gnomAD frequencies, and ancestry-aware context. Generates prioritised variant reports.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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nonlinear-solvers
Select and configure nonlinear solvers for f(x)=0 or min F(x). Use for Newton methods, quasi-Newton (BFGS, L-BFGS), Broyden, Anderson acceleration, diagnosing convergence issues, choosing line search vs trust region, and analyzing Jacobian quality.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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chemist-analyst
Analyzes events through chemistry lens using molecular structure, reaction mechanisms, thermodynamics,
kinetics, and analytical techniques (spectroscopy, chromatography, mass spectrometry).
Provides insights on chemical processes, material properties, reaction pathways, synthesis, and analytical methods.
Use when: Chemical reactions, material analysis, synthesis planning, process optimization, environmental chemistry.
Evaluates: Molecular structure, reaction mechanisms, yield, selectivity, safety, environmental impact.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-intervals-gtf-gff-handling
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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research-literature
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-alignment-io
Read, write, and convert multiple sequence alignment files using Biopython Bio.AlignIO. Supports Clustal, PHYLIP, Stockholm, FASTA, Nexus, and other alignment formats for phylogenetics and conservation analysis. Use when reading, writing, or converting alignment file formats.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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biokernel
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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test-driven-development
Use when implementing any feature or bugfix, before writing implementation code
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-de-results
Extract, filter, annotate, and export differential expression results from DESeq2 or edgeR. Use for identifying significant genes, applying multiple testing corrections, adding gene annotations, and preparing results for downstream analysis. Use when filtering and exporting DE analysis results.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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biomni-research-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-intervals-proximity-operations
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-imaging-mass-cytometry-spatial-analysis
Spatial analysis of cell neighborhoods and interactions in IMC data. Covers neighbor graphs, spatial statistics, and interaction testing. Use when analyzing spatial relationships between cell types, testing for neighborhood enrichment, or identifying cell-cell interaction patterns in imaging mass cytometry data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-hi-c-analysis-matrix-operations
Balance, normalize, and transform Hi-C contact matrices using cooler and cooltools. Apply iterative correction (ICE), compute expected values, and generate observed/expected matrices. Use when normalizing or transforming Hi-C matrices.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-proteomics-differential-abundance
Statistical testing for differentially abundant proteins between conditions. Covers limma and MSstats workflows with multiple testing correction. Use when identifying proteins with significant abundance changes between experimental groups.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-longread-qc
Quality control for long-read sequencing data using NanoPlot, NanoStat, and chopper. Generate QC reports, filter reads by length and quality, and visualize read characteristics. Use when assessing ONT or PacBio run quality or filtering reads before assembly or alignment.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-liquid-biopsy-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-metabolomics-msdial-preprocessing
MS-DIAL-based metabolomics preprocessing as alternative to XCMS. Covers peak detection, alignment, annotation, and export for downstream analysis. Use when processing MS-DIAL output files for R/Python analysis or when preferring GUI-based preprocessing.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009