Topic: openclaw
3,425 skills in this topic.
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bio-phylo-tree-manipulation
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-intervals-bigwig-tracks
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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boltzgen
All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusion (not just backbone), (4) Require precise binding geometries, (5) Using YAML-based configuration.
For backbone-only generation, use rfdiffusion. For sequence-only design, use proteinmpnn. For structure validation, use boltz.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-genome-browser-tracks
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-phylo-modern-tree-inference
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-phylo-distance-calculations
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-phasing-imputation-reference-panels
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-phasing-imputation-haplotype-phasing
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-expression-to-pathways
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-alignment-filtering
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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antibody-design-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-orchestrator
Meta-agent that routes bioinformatics requests to specialised sub-skills. Handles file type detection, analysis planning, report generation, and reproducibility export.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bioinformatics-singlecell
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bindingdb-database
Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50). Search by target (UniProt ID), compound (SMILES/name), or pathogen. Essential for drug discovery, lead optimization, polypharmacology analysis, and structure-activity relationship (SAR) studies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-fragment-analysis
Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin. Extracts nucleosome positioning patterns, fragment ratios, and DELFI-style fragmentation profiles for cancer detection. Use when leveraging fragment patterns for tumor detection or tissue-of-origin analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflow-management-snakemake-workflows
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bindcraft
End-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using different design protocols (fast, default, slow), (4) Need joint backbone and sequence optimization, (5) Want high experimental success rate.
For backbone-only generation, use rfdiffusion. For QC thresholds, use protein-qc. For tool selection guidance, use binder-design.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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binder-design
Guidance for choosing the right protein binder design tool. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types.
For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-gatk-variant-calling
Variant calling with GATK HaplotypeCaller following best practices. Covers germline SNP/indel calling, GVCF workflow for cohorts, joint genotyping, and variant quality score recalibration (VQSR). Use when calling variants with GATK HaplotypeCaller.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-multi-omics-mofa-integration
Multi-Omics Factor Analysis (MOFA2) for unsupervised integration of multiple data modalities. Identifies shared and view-specific sources of variation. Use when integrating RNA-seq, proteomics, methylation, or other omics to discover latent factors driving biological variation across modalities.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-epitranscriptomics-m6anet-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-pdb-structure-io
Parse and write protein structure files using Biopython Bio.PDB. Use when reading PDB, mmCIF, and MMTF files, downloading structures from RCSB PDB, or writing structures to various formats.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-atac-seq-atac-peak-calling
Call accessible chromatin regions from ATAC-seq data using MACS3 with ATAC-specific parameters. Use when identifying open chromatin regions from aligned ATAC-seq BAM files, different from ChIP-seq peak calling.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-experimental-design-multiple-testing
FreedomIntelligence/OpenClaw-Medical-Skills 2,009