Topic: openclaw
3,425 skills in this topic.
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tooluniverse-precision-medicine-stratification
Comprehensive patient stratification for precision medicine by integrating genomic, clinical, and therapeutic data. Given a disease/condition, genomic data (germline variants, somatic mutations, expression), and optional clinical parameters, performs multi-phase analysis across 9 phases covering disease disambiguation, genetic risk assessment, disease-specific molecular stratification, pharmacogenomic profiling, comorbidity/DDI risk, pathway analysis, clinical evidence and guideline mapping, clinical trial matching, and integrated outcome prediction. Generates a quantitative Precision Medicine Risk Score (0-100) with risk tier assignment (Low/Intermediate/High/Very High), treatment algorithm (1st/2nd/3rd line), pharmacogenomic guidance, clinical trial matches, and monitoring plan. Use when clinicians ask about patient risk stratification, treatment selection, prognosis prediction, or personalized therapeutic strategy across cancer, metabolic, cardiovascular, neurological, or rare diseases.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-ctdna-mutation-detection
Detects somatic mutations in circulating tumor DNA using variant callers optimized for low allele fractions with UMI-based error suppression. Reliably detects mutations at VAF above 0.5 percent using consensus-based approaches. Use when identifying tumor mutations from plasma DNA or tracking specific variants.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-multipanel-figures
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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paper-2-web
This skill should be used when converting academic papers into promotional and presentation formats including interactive websites (Paper2Web), presentation videos (Paper2Video), and conference posters (Paper2Poster). Use this skill for tasks involving paper dissemination, conference preparation, creating explorable academic homepages, generating video abstracts, or producing print-ready posters from LaTeX or PDF sources.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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trial-eligibility-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-molecular-io
Reads, writes, and converts molecular file formats (SMILES, SDF, MOL2, PDB) using RDKit and Open Babel. Handles structure parsing, canonicalization, and full standardization pipeline including sanitization, normalization, and tautomer canonicalization. Use when loading chemical libraries, converting formats, or preparing molecules for analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-variant-calling-structural-variant-calling
Call structural variants (SVs) from short-read sequencing using Manta, Delly, and LUMPY. Detects deletions, insertions, inversions, duplications, and translocations that are too large for standard SNV callers. Use when detecting structural variants from short-read data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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modern-drug-rehab-computer
Comprehensive knowledge system for addiction recovery environments, supporting both residential and outpatient (IOP/PHP) patients. Expert in evidence-based treatment modalities (CBT, DBT, MI, EMDR, MAT), recovery resources, coping strategies, crisis intervention, family systems, and holistic wellness. Activate on "rehab", "addiction recovery", "substance abuse", "treatment center", "IOP", "PHP", "detox", "sobriety support", "MAT", "Suboxone", "methadone", "12 step", "SMART Recovery". NOT for prescribing medications (consult medical professionals), emergency overdose situations (call 911), or replacing licensed counselors/therapists.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tcm-constitution-analyzer
分析中医体质数据、识别体质类型、评估体质特征,并提供个性化养生建议。支持与营养、运动、睡眠等健康数据的关联分析。
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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nutrition-analyzer
分析营养数据、识别营养模式、评估营养状况，并提供个性化营养建议。支持与运动、睡眠、慢性病数据的关联分析。
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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gtars
High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection, tokenization for ML models, or fragment analysis in computational genomics and machine learning applications.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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biopython
Primary Python toolkit for molecular biology. Preferred for Python-based PubMed/NCBI queries (Bio.Entrez), sequence manipulation, file parsing (FASTA, GenBank, FASTQ, PDB), advanced BLAST workflows, structures, phylogenetics. For quick BLAST, use gget. For direct REST API, use pubmed-database.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-atac-seq-differential-accessibility
Find differentially accessible chromatin regions between conditions using DiffBind or DESeq2. Use when comparing chromatin accessibility between treatment groups, cell types, or developmental stages in ATAC-seq experiments.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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solublempnn
Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation.
For standard design, use proteinmpnn. For ligand-aware design, use ligandmpnn.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-format-conversion
Convert between sequence file formats (FASTA, FASTQ, GenBank, EMBL) using Biopython Bio.SeqIO. Use when changing file formats or preparing data for different tools.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-cytometry-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-sequence-statistics
Calculate sequence statistics (N50, length distribution, GC content, summary reports) using Biopython. Use when analyzing sequence datasets, generating QC reports, or comparing assemblies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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consensus-sequences
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-microbiome-qiime2-workflow
QIIME2 command-line workflow for 16S/ITS amplicon analysis. Alternative to DADA2/phyloseq R workflow with built-in provenance tracking. Use when preferring CLI over R, needing reproducible provenance, or working within QIIME2 ecosystem.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-specialized-omics-plots
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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jaspar-database
Query JASPAR for transcription factor binding site (TFBS) profiles (PWMs/PFMs). Search by TF name, species, or class; scan DNA sequences for TF binding sites; compare matrices; essential for regulatory genomics, motif analysis, and GWAS regulatory variant interpretation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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variant-normalization
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-read-alignment-bowtie2-alignment
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-de-visualization
Visualize differential expression results using DESeq2/edgeR built-in functions. Covers plotMA, plotDispEsts, plotCounts, plotBCV, sample distance heatmaps, and p-value histograms. Use when visualizing differential expression results.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009