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Topic: openclaw

3,425 skills in this topic.

bio-genome-assembly-assembly-qc
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflows-clip-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
prs-net-deep-learning-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-clinical-databases-somatic-signatures Extract and analyze mutational signatures from somatic variants using SigProfiler or MutationalPatterns to characterize mutagenic processes. Use when identifying DNA damage mechanisms or etiology in cancer genomes.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tooluniverse-pharmacovigilance Analyze drug safety signals from FDA adverse event reports, label warnings, and pharmacogenomic data. Calculates disproportionality measures (PRR, ROR), identifies serious adverse events, assesses pharmacogenomic risk variants. Use when asked about drug safety, adverse events, post-market surveillance, or risk-benefit assessment.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-hi-c-analysis-hic-differential Compare Hi-C contact matrices between conditions to identify differential chromatin interactions. Compute log2 fold changes, statistical significance, and visualize differential contact maps. Use when comparing Hi-C contacts between conditions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
gwas-database Query NHGRI-EBI GWAS Catalog for SNP-trait associations. Search variants by rs ID, disease/trait, gene, retrieve p-values and summary statistics, for genetic epidemiology and polygenic risk scores.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
medical-imaging-review Write comprehensive literature reviews for medical imaging AI research. Use when writing survey papers, systematic reviews, or literature analyses on topics like segmentation, detection, classification in CT, MRI, X-ray, ultrasound, or pathology imaging. Triggers on requests for "review paper", "survey", "literature review", "综述", "systematic review", or mentions of writing academic reviews on deep learning for medical imaging.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
pdb Fetch and analyze protein structures from RCSB PDB. Use this skill when: (1) Need to download a structure by PDB ID, (2) Search for similar structures, (3) Prepare target for binder design, (4) Extract specific chains or domains, (5) Get structure metadata. For sequence lookup, use uniprot. For binder design workflow, use binder-design.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tooluniverse-immunotherapy-response-prediction Predict patient response to immune checkpoint inhibitors (ICIs) using multi-biomarker integration. Given a cancer type, somatic mutations, and optional biomarkers (TMB, PD-L1, MSI status), performs systematic analysis across 11 phases covering TMB classification, neoantigen burden estimation, MSI/MMR assessment, PD-L1 evaluation, immune microenvironment profiling, mutation-based resistance/sensitivity prediction, clinical evidence retrieval, and multi-biomarker score integration. Generates a quantitative ICI Response Score (0-100), response likelihood tier, specific ICI drug recommendations with evidence, resistance risk factors, and a monitoring plan. Use when oncologists ask about immunotherapy eligibility, checkpoint inhibitor selection, or biomarker-guided ICI treatment decisions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-alignment-sorting
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
agentd-drug-discovery
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-causal-genomics-colocalization-analysis Test whether two traits share a causal variant at a genomic locus using Bayesian colocalization with coloc. Computes posterior probabilities for shared vs distinct causal variants between GWAS and eQTL signals. Use when determining if a GWAS signal and an eQTL share the same causal variant.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
adaptyv Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
alphafold Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm. For QC thresholds, use protein-qc.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-alignment-files-bam-statistics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-atac-seq-atac-qc Quality control metrics for ATAC-seq data including fragment size distribution, TSS enrichment, FRiP, and library complexity. Use when assessing ATAC-seq library quality before or after peak calling to identify problematic samples.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-comparative-genomics-hgt-detection
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-chipseq-differential-binding Differential binding analysis using DiffBind. Compare ChIP-seq peaks between conditions with statistical rigor. Requires replicate samples. Outputs differentially bound regions with fold changes and p-values. Use when comparing ChIP-seq binding between conditions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-clip-seq-clip-preprocessing
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-clinical-databases-hla-typing Call HLA alleles from NGS data using OptiType, HLA-HD, or arcasHLA for immunogenomics applications. Use when determining HLA genotype for transplant matching, neoantigen prediction, or pharmacogenomic screening.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-consensus-sequences Generate consensus FASTA sequences by applying VCF variants to a reference using bcftools consensus. Use when creating sample-specific reference sequences or reconstructing haplotypes.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-codon-usage
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-chipseq-motif-analysis De novo motif discovery and known motif enrichment analysis using HOMER and MEME-ChIP. Identify transcription factor binding motifs in ChIP-seq, ATAC-seq, or other genomic peak data. Use when finding enriched DNA motifs in peak sequences.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009