Topic: openclaw-skills
1,539 skills in this topic.
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bio-workflows-hic-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-crispr-screen-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-engineering-off-target-prediction
Predict CRISPR off-target sites using Cas-OFFinder and CFD scoring algorithms. Identify potential unintended cleavage sites genome-wide and assess guide specificity. Use when evaluating guide RNA specificity or selecting guides with minimal off-target risk.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-chipseq-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-biomarker-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-sequence-slicing
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-vcf-manipulation
Merge, concatenate, sort, intersect, and subset VCF files using bcftools. Use when combining variant files, comparing call sets, or restructuring VCF data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-similarity-searching
Performs molecular similarity searches using Tanimoto coefficient on fingerprints via RDKit. Finds structurally similar compounds using ECFP or MACCS keys and clusters molecules by structural similarity using Butina clustering. Use when finding analogs of a query compound or clustering chemical libraries.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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scvi-tools
This skill should be used when working with single-cell omics data analysis using scvi-tools, including scRNA-seq, scATAC-seq, CITE-seq, spatial transcriptomics, and other single-cell modalities. Use this skill for probabilistic modeling, batch correction, dimensionality reduction, differential expression, cell type annotation, multimodal integration, and spatial analysis tasks.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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scikit-survival
Comprehensive toolkit for survival analysis and time-to-event modeling in Python using scikit-survival. Use this skill when working with censored survival data, performing time-to-event analysis, fitting Cox models, Random Survival Forests, Gradient Boosting models, or Survival SVMs, evaluating survival predictions with concordance index or Brier score, handling competing risks, or implementing any survival analysis workflow with the scikit-survival library.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-spatial-preprocessing
Quality control, filtering, normalization, and feature selection for spatial transcriptomics data. Calculate QC metrics, filter spots/cells, normalize counts, and identify highly variable genes. Use when filtering and normalizing spatial transcriptomics data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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scikit-bio
Biological data toolkit. Sequence analysis, alignments, phylogenetic trees, diversity metrics (alpha/beta, UniFrac), ordination (PCoA), PERMANOVA, FASTA/Newick I/O, for microbiome analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-sra-data
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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scientific-writing
Core skill for the deep research and writing tool. Write scientific manuscripts in full paragraphs (never bullet points). Use two-stage process: (1) create section outlines with key points using research-lookup, (2) convert to flowing prose. IMRAD structure, citations (APA/AMA/Vancouver), figures/tables, reporting guidelines (CONSORT/STROBE/PRISMA), for research papers and journal submissions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-substructure-search
Searches molecular libraries for substructure matches using SMARTS patterns with RDKit. Filters compounds by pharmacophore features, functional groups, or scaffold matches with atom mapping. Use when finding compounds containing specific chemical moieties or filtering libraries by structural features.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-intervals-interval-arithmetic
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-image-analysis
Process and analyze tissue images from spatial transcriptomics data using Squidpy. Extract image features, segment cells/nuclei, and compute morphological features from H&E or IF images. Use when processing tissue images for spatial transcriptomics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-systems-biology-flux-balance-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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usmle
Prepare for US medical licensing exams with progress tracking, weak area analysis, question bank management, and residency match planning.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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scientific-slides
Build slide decks and presentations for research talks. Use this for making PowerPoint slides, conference presentations, seminar talks, research presentations, thesis defense slides, or any scientific talk. Provides slide structure, design templates, timing guidance, and visual validation. Works with PowerPoint and LaTeX Beamer.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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seq-wrangler
Sequence QC, alignment, and BAM processing. Wraps FastQC, BWA/Bowtie2, SAMtools for automated read-to-BAM pipelines.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-tumor-fraction-estimation
Estimates circulating tumor DNA fraction from shallow whole-genome sequencing using ichorCNA. Detects copy number alterations via HMM segmentation and calculates ctDNA percentage. Requires 0.1-1x sWGS coverage. Use when quantifying tumor burden from liquid biopsy or monitoring treatment response.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-variant-calling
Call SNPs and indels from aligned reads using bcftools mpileup and call. Use when detecting variants from BAM files or generating VCF from alignments.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-hi-c-analysis-hic-data-io
Load, convert, and manipulate Hi-C contact matrices using cooler format. Read .cool/.mcool files, convert from .hic format, access matrix data, and export to different formats. Use when loading or converting Hi-C contact matrices.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009