Topic: openclaw-skills
1,539 skills in this topic.
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bio-fastq-quality
Work with FASTQ quality scores using Biopython. Use when analyzing read quality, filtering by quality, trimming low-quality bases, or generating quality reports.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-atac-seq-atac-peak-calling
Call accessible chromatin regions from ATAC-seq data using MACS3 with ATAC-specific parameters. Use when identifying open chromatin regions from aligned ATAC-seq BAM files, different from ChIP-seq peak calling.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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aav-vector-design-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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galaxy-bridge
Galaxy tool discovery, intelligent recommendation, and execution — 8,000+ bioinformatics tools from usegalaxy.org with multi-signal scoring and workflow suggestions
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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glycoengineering
Analyze and engineer protein glycosylation. Scan sequences for N-glycosylation sequons (N-X-S/T), predict O-glycosylation hotspots, and access curated glycoengineering tools (NetOGlyc, GlycoShield, GlycoWorkbench). For glycoprotein engineering, therapeutic antibody optimization, and vaccine design.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tumor-heterogeneity-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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profile-report
Unified personal genomic profile report — reads a PatientProfile JSON and synthesizes all skill results into a single "Your Genomic Profile" document.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-intervals-bigwig-tracks
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-genome-browser-tracks
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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prior-auth-review-skill
Automate payer review of prior authorization (PA) requests. This skill should be used when users say "Review this PA request", "Process prior authorization for [procedure]", "Assess medical necessity", "Generate PA decision", or when processing clinical documentation for coverage policy validation and authorization decisions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-experimental-design-multiple-testing
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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gwas-prs
Calculate polygenic risk scores from DTC genetic data using the PGS Catalog
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-alignment-filtering
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bindingdb-database
Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50). Search by target (UniProt ID), compound (SMILES/name), or pathogen. Essential for drug discovery, lead optimization, polypharmacology analysis, and structure-activity relationship (SAR) studies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-single-cell
Production-ready single-cell and expression matrix analysis using scanpy, anndata, and scipy. Performs scRNA-seq QC, normalization, PCA, UMAP, Leiden/Louvain clustering, differential expression (Wilcoxon, t-test, DESeq2), cell type annotation, per-cell-type statistical analysis, gene-expression correlation, batch correction (Harmony), trajectory inference, and cell-cell communication analysis. NEW: Analyzes ligand-receptor interactions between cell types using OmniPath (CellPhoneDB, CellChatDB), scores communication strength, identifies signaling cascades, and handles multi-subunit receptor complexes. Integrates with ToolUniverse gene annotation tools (HPA, Ensembl, MyGene, UniProt) and enrichment tools (gseapy, PANTHER, STRING). Supports h5ad, 10X, CSV/TSV count matrices, and pre-annotated datasets. Use when analyzing single-cell RNA-seq data, studying cell-cell interactions, performing cell type differential expression, computing gene-expression correlations by cell type, analyzing tumor-immune communication, or answering questions about scRNA-seq datasets.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-metabolomics-targeted-analysis
Targeted metabolomics analysis using MRM/SRM with standard curves. Covers absolute quantification, method validation, and quality assessment. Use when quantifying specific metabolites using calibration curves and internal standards.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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crispr-offtarget-predictor
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-spatial-omics-analysis
Computational analysis framework for spatial multi-omics data integration. Given spatially variable genes (SVGs), spatial domain annotations, tissue type, and disease context from spatial transcriptomics/proteomics experiments (10x Visium, MERFISH, DBiTplus, SLIDE-seq, etc.), performs comprehensive biological interpretation including pathway enrichment, cell-cell interaction inference, druggable target identification, immune microenvironment characterization, and multi-modal integration. Produces a detailed markdown report with Spatial Omics Integration Score (0-100), domain-by-domain characterization, and validation recommendations. Uses 70+ ToolUniverse tools across 9 analysis phases. Use when users ask about spatial transcriptomics analysis, spatial omics interpretation, tissue heterogeneity, spatial gene expression patterns, tumor microenvironment mapping, tissue zonation, or cell-cell communication from spatial data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-adverse-event-detection
Detect and analyze adverse drug event signals using FDA FAERS data, drug labels, disproportionality analysis (PRR, ROR, IC), and biomedical evidence. Generates quantitative safety signal scores (0-100) with evidence grading. Use for post-market surveillance, pharmacovigilance, drug safety assessment, adverse event investigation, and regulatory decision support.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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boltzgen
All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusion (not just backbone), (4) Require precise binding geometries, (5) Using YAML-based configuration.
For backbone-only generation, use rfdiffusion. For sequence-only design, use proteinmpnn. For structure validation, use boltz.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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cellagent-annotation
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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clinical-reports
Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), and patient documentation (SOAP, H&P, discharge summaries). Full support with templates, regulatory compliance (HIPAA, FDA, ICH-GCP), and validation tools.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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chembl-search
Search ChEMBL bioactive molecules database with natural language queries. Find compounds and assay data with Valyu semantic search.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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claims-appeals
FreedomIntelligence/OpenClaw-Medical-Skills 2,009