Topic: openclaw-skills
1,539 skills in this topic.
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bio-entrez-fetch
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-fragment-analysis
Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin. Extracts nucleosome positioning patterns, fragment ratios, and DELFI-style fragmentation profiles for cancer detection. Use when leveraging fragment patterns for tumor detection or tissue-of-origin analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bindingdb-database
Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50). Search by target (UniProt ID), compound (SMILES/name), or pathogen. Essential for drug discovery, lead optimization, polypharmacology analysis, and structure-activity relationship (SAR) studies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-flow-cytometry-gating-analysis
Manual and automated gating for defining cell populations in flow cytometry. Covers rectangular, polygon, and data-driven gates. Use when identifying cell populations through hierarchical gating strategies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-differential-expression-timeseries-de
Analyze time-series RNA-seq data using limma voom with splines, maSigPro, and ImpulseDE2. Identify genes with dynamic expression patterns. Use when analyzing time-series or longitudinal expression data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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neurokit2
Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements. Applicable for heart rate variability analysis, event-related potentials, complexity measures, autonomic nervous system assessment, psychophysiology research, and multi-modal physiological signal integration.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-causal-genomics-mediation-analysis
Decompose genetic effects into direct and indirect paths through mediating variables using the mediation R package. Tests whether gene expression, methylation, or other molecular phenotypes mediate the effect of genetic variants on disease. Use when testing whether a molecular phenotype mediates the genotype-to-phenotype relationship.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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virtual-lab-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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radgpt-radiology-reporter
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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regulatory-drafting
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tcga-bulk-data-preprocessing-with-omicverse
Guide Claude through ingesting TCGA sample sheets, expression archives, and clinical carts into omicverse, initialising survival metadata, and exporting annotated AnnData files.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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galaxy-bridge
Galaxy tool discovery, intelligent recommendation, and execution — 8,000+ bioinformatics tools from usegalaxy.org with multi-signal scoring and workflow suggestions
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-de-deseq2-basics
Perform differential expression analysis using DESeq2 in R/Bioconductor. Use for analyzing RNA-seq count data, creating DESeqDataSet objects, running the DESeq workflow, and extracting results with log fold change shrinkage. Use when performing DE analysis with DESeq2.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-flow-cytometry-clustering-phenotyping
Unsupervised clustering and cell type identification for flow/mass cytometry. Covers FlowSOM, Phenograph, and CATALYST workflows. Use when discovering cell populations in high-dimensional cytometry data without predefined gates.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-data-visualization-volcano-customization
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-filter-sequences
Filter and select sequences by criteria (length, ID, GC content, patterns) using Biopython. Use when subsetting sequences, removing unwanted records, or selecting by specific criteria.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-single-cell
Production-ready single-cell and expression matrix analysis using scanpy, anndata, and scipy. Performs scRNA-seq QC, normalization, PCA, UMAP, Leiden/Louvain clustering, differential expression (Wilcoxon, t-test, DESeq2), cell type annotation, per-cell-type statistical analysis, gene-expression correlation, batch correction (Harmony), trajectory inference, and cell-cell communication analysis. NEW: Analyzes ligand-receptor interactions between cell types using OmniPath (CellPhoneDB, CellChatDB), scores communication strength, identifies signaling cascades, and handles multi-subunit receptor complexes. Integrates with ToolUniverse gene annotation tools (HPA, Ensembl, MyGene, UniProt) and enrichment tools (gseapy, PANTHER, STRING). Supports h5ad, 10X, CSV/TSV count matrices, and pre-annotated datasets. Use when analyzing single-cell RNA-seq data, studying cell-cell interactions, performing cell type differential expression, computing gene-expression correlations by cell type, analyzing tumor-immune communication, or answering questions about scRNA-seq datasets.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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clinical-diagnostic-reasoning
Identify and counteract cognitive biases in medical decision-making through systematic error analysis and contextual algorithm application. For diagnostic reasoning, treatment decisions, and clinical judgment improvement. NOT for basic medical knowledge, technical procedures, or non-clinical healthcare domains.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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aav-vector-design-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-spatial-omics-analysis
Computational analysis framework for spatial multi-omics data integration. Given spatially variable genes (SVGs), spatial domain annotations, tissue type, and disease context from spatial transcriptomics/proteomics experiments (10x Visium, MERFISH, DBiTplus, SLIDE-seq, etc.), performs comprehensive biological interpretation including pathway enrichment, cell-cell interaction inference, druggable target identification, immune microenvironment characterization, and multi-modal integration. Produces a detailed markdown report with Spatial Omics Integration Score (0-100), domain-by-domain characterization, and validation recommendations. Uses 70+ ToolUniverse tools across 9 analysis phases. Use when users ask about spatial transcriptomics analysis, spatial omics interpretation, tissue heterogeneity, spatial gene expression patterns, tumor microenvironment mapping, tissue zonation, or cell-cell communication from spatial data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-fastq-quality
Work with FASTQ quality scores using Biopython. Use when analyzing read quality, filtering by quality, trimming low-quality bases, or generating quality reports.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-intervals-bigwig-tracks
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-read-alignment-hisat2-alignment
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-adverse-event-detection
Detect and analyze adverse drug event signals using FDA FAERS data, drug labels, disproportionality analysis (PRR, ROR, IC), and biomedical evidence. Generates quantitative safety signal scores (0-100) with evidence grading. Use for post-market surveillance, pharmacovigilance, drug safety assessment, adverse event investigation, and regulatory decision support.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009