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Topic: clawhub

924 skills in this topic.

bio-isoform-switching Analyzes isoform switching events and functional consequences using IsoformSwitchAnalyzeR. Predicts protein domain changes, NMD sensitivity, ORF alterations, and coding potential shifts between conditions. Use when investigating how splicing changes affect protein function.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tooluniverse-multi-omics-integration Integrate and analyze multiple omics datasets (transcriptomics, proteomics, epigenomics, genomics, metabolomics) for systems biology and precision medicine. Performs cross-omics correlation, multi-omics clustering (MOFA+, NMF), pathway-level integration, and sample matching. Coordinates ToolUniverse skills for expression data (RNA-seq), epigenomics (methylation, ChIP-seq), variants (SNVs, CNVs), protein interactions, and pathway enrichment. Use when analyzing multi-omics datasets, performing integrative analysis, discovering multi-omics biomarkers, studying disease mechanisms across molecular layers, or conducting systems biology research that requires coordinated analysis of transcriptome, genome, epigenome, proteome, and metabolome data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tooluniverse-metabolomics-analysis Analyze metabolomics data including metabolite identification, quantification, pathway analysis, and metabolic flux. Processes LC-MS, GC-MS, NMR data from targeted and untargeted experiments. Performs normalization, statistical analysis, pathway enrichment, metabolite-enzyme integration, and biomarker discovery. Use when analyzing metabolomics datasets, identifying differential metabolites, studying metabolic pathways, integrating with transcriptomics/proteomics, discovering metabolic biomarkers, performing flux balance analysis, or characterizing metabolic phenotypes in disease, drug response, or physiological conditions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-sequence-properties
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-sequence-statistics Calculate sequence statistics (N50, length distribution, GC content, summary reports) using Biopython. Use when analyzing sequence datasets, generating QC reports, or comparing assemblies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
labarchive-integration Electronic lab notebook API integration. Access notebooks, manage entries/attachments, backup notebooks, integrate with Protocols.io/Jupyter/REDCap, for programmatic ELN workflows.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
filtering-best-practices
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-single-cell-cell-communication Infer cell-cell communication networks from scRNA-seq data using CellChat, NicheNet, and LIANA for ligand-receptor interaction analysis. Use when inferring ligand-receptor interactions between cell types.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-immunoinformatics-immunogenicity-scoring Score and prioritize neoantigens and epitopes for immunogenicity using multi-factor models combining MHC binding, processing, expression, and sequence features. Rank candidates for vaccine design. Use when prioritizing epitopes for vaccine development or identifying the most immunogenic neoantigens.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
deepvariant
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
consensus-sequences
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
jaspar-database Query JASPAR for transcription factor binding site (TFBS) profiles (PWMs/PFMs). Search by TF name, species, or class; scan DNA sequences for TF binding sites; compare matrices; essential for regulatory genomics, motif analysis, and GWAS regulatory variant interpretation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-microbiome-qiime2-workflow QIIME2 command-line workflow for 16S/ITS amplicon analysis. Alternative to DADA2/phyloseq R workflow with built-in provenance tracking. Use when preferring CLI over R, needing reproducible provenance, or working within QIIME2 ecosystem.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
clinical-interpretation
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
pydeseq2 Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
torch-geometric Graph Neural Networks (PyG). Node/graph classification, link prediction, GCN, GAT, GraphSAGE, heterogeneous graphs, molecular property prediction, for geometric deep learning.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-spatial-transcriptomics-spatial-visualization Visualize spatial transcriptomics data using Squidpy and Scanpy. Create tissue plots with gene expression, clusters, and annotations overlaid on histology images. Use when visualizing spatial expression patterns.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-splicing-qc Assesses RNA-seq data quality for splicing analysis including junction saturation curves, splice site strength scoring, and junction coverage metrics using RSeQC. Use when evaluating data suitability for splicing analysis or troubleshooting low event detection.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-genome-intervals-bed-file-basics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-structural-biology-modern-structure-prediction Predict protein structures using modern ML models including AlphaFold3, ESMFold, Chai-1, and Boltz-1. Use when predicting structures for novel proteins, protein complexes, or when comparing predictions across multiple methods.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
gwas-lookup Federated variant lookup across 9 genomic databases — GWAS Catalog, Open Targets, PheWeb (UKB, FinnGen, BBJ), GTEx, eQTL Catalogue, and more.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-phylo-tree-io
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
wikipedia-search Search and fetch structured content from Wikipedia using the MediaWiki API for reliable, encyclopedic information
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
modern-drug-rehab-computer Comprehensive knowledge system for addiction recovery environments, supporting both residential and outpatient (IOP/PHP) patients. Expert in evidence-based treatment modalities (CBT, DBT, MI, EMDR, MAT), recovery resources, coping strategies, crisis intervention, family systems, and holistic wellness. Activate on "rehab", "addiction recovery", "substance abuse", "treatment center", "IOP", "PHP", "detox", "sobriety support", "MAT", "Suboxone", "methadone", "12 step", "SMART Recovery". NOT for prescribing medications (consult medical professionals), emergency overdose situations (call 911), or replacing licensed counselors/therapists.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009