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Topic: clawhub

924 skills in this topic.

bio-immunoinformatics-immunogenicity-scoring Score and prioritize neoantigens and epitopes for immunogenicity using multi-factor models combining MHC binding, processing, expression, and sequence features. Rank candidates for vaccine design. Use when prioritizing epitopes for vaccine development or identifying the most immunogenic neoantigens.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-single-cell-cell-communication Infer cell-cell communication networks from scRNA-seq data using CellChat, NicheNet, and LIANA for ligand-receptor interaction analysis. Use when inferring ligand-receptor interactions between cell types.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
filtering-best-practices
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
labarchive-integration Electronic lab notebook API integration. Access notebooks, manage entries/attachments, backup notebooks, integrate with Protocols.io/Jupyter/REDCap, for programmatic ELN workflows.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-sequence-statistics Calculate sequence statistics (N50, length distribution, GC content, summary reports) using Biopython. Use when analyzing sequence datasets, generating QC reports, or comparing assemblies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-sequence-properties
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tooluniverse-metabolomics-analysis Analyze metabolomics data including metabolite identification, quantification, pathway analysis, and metabolic flux. Processes LC-MS, GC-MS, NMR data from targeted and untargeted experiments. Performs normalization, statistical analysis, pathway enrichment, metabolite-enzyme integration, and biomarker discovery. Use when analyzing metabolomics datasets, identifying differential metabolites, studying metabolic pathways, integrating with transcriptomics/proteomics, discovering metabolic biomarkers, performing flux balance analysis, or characterizing metabolic phenotypes in disease, drug response, or physiological conditions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tooluniverse-multi-omics-integration Integrate and analyze multiple omics datasets (transcriptomics, proteomics, epigenomics, genomics, metabolomics) for systems biology and precision medicine. Performs cross-omics correlation, multi-omics clustering (MOFA+, NMF), pathway-level integration, and sample matching. Coordinates ToolUniverse skills for expression data (RNA-seq), epigenomics (methylation, ChIP-seq), variants (SNVs, CNVs), protein interactions, and pathway enrichment. Use when analyzing multi-omics datasets, performing integrative analysis, discovering multi-omics biomarkers, studying disease mechanisms across molecular layers, or conducting systems biology research that requires coordinated analysis of transcriptome, genome, epigenome, proteome, and metabolome data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-isoform-switching Analyzes isoform switching events and functional consequences using IsoformSwitchAnalyzeR. Predicts protein domain changes, NMD sensitivity, ORF alterations, and coding potential shifts between conditions. Use when investigating how splicing changes affect protein function.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-variant-calling-structural-variant-calling Call structural variants (SVs) from short-read sequencing using Manta, Delly, and LUMPY. Detects deletions, insertions, inversions, duplications, and translocations that are too large for standard SNV callers. Use when detecting structural variants from short-read data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-methylation-dmr-detection Differentially methylated region (DMR) detection using methylKit tiles, bsseq BSmooth, and DMRcate. Use when identifying contiguous genomic regions with methylation differences between experimental conditions or cell types.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-rna-quantification-tximport-workflow
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-rna-quantification-featurecounts-counting
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-proteomics-data-import Load and parse mass spectrometry data formats including mzML, mzXML, and quantification tool outputs like MaxQuant proteinGroups.txt. Use when starting a proteomics analysis with raw or processed MS data. Handles contaminant filtering and missing value assessment.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
verification-before-completion Use when about to claim work is complete, fixed, or passing, before committing or creating PRs - requires running verification commands and confirming output before making any success claims; evidence before assertions always
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
gatk-variant-calling
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-read-qc-adapter-trimming Remove sequencing adapters from FASTQ files using Cutadapt and Trimmomatic. Supports single-end and paired-end reads, Illumina TruSeq, Nextera, and custom adapter sequences. Use when FastQC shows adapter contamination or before alignment of short reads.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-reference-operations
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
pysam Genomic file toolkit. Read/write SAM/BAM/CRAM alignments, VCF/BCF variants, FASTA/FASTQ sequences, extract regions, calculate coverage, for NGS data processing pipelines.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
variant-normalization
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-read-qc-fastp-workflow All-in-one read preprocessing with fastp including adapter trimming, quality filtering, deduplication, base correction, and HTML report generation. Use when preprocessing Illumina data and wanting a single fast tool instead of separate Cutadapt, Trimmomatic, and FastQC steps.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
vcf-basics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
vcf-statistics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-read-alignment-bowtie2-alignment
FreedomIntelligence/OpenClaw-Medical-Skills 2,009