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Topic: skills

17,247 skills in this topic.

bio-gatk-variant-calling Variant calling with GATK HaplotypeCaller following best practices. Covers germline SNP/indel calling, GVCF workflow for cohorts, joint genotyping, and variant quality score recalibration (VQSR). Use when calling variants with GATK HaplotypeCaller.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-single-cell-lineage-tracing Reconstruct cell lineage trees from CRISPR barcode tracing or mitochondrial mutations. Use when studying clonal dynamics, cell fate decisions, or developmental trajectories.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
lobster-bioinformatics Run bioinformatics analyses using Lobster AI - single-cell RNA-seq, bulk RNA-seq, literature mining, dataset discovery, quality control, and visualization. Use when analyzing genomics data, searching for papers/datasets, or working with H5AD, CSV, GEO/SRA accessions, or biological data. Requires lobster-ai package installed.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-fragment-analysis Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin. Extracts nucleosome positioning patterns, fragment ratios, and DELFI-style fragmentation profiles for cancer detection. Use when leveraging fragment patterns for tumor detection or tissue-of-origin analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-systems-biology-gene-essentiality
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-data-visualization-volcano-customization
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-imaging-mass-cytometry-quality-metrics Quality metrics for IMC data including signal-to-noise, channel correlation, tissue integrity, and acquisition QC. Use when assessing data quality before analysis or troubleshooting problematic acquisitions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
single-cell-downstream-analysis Checklist-style reference for OmicVerse downstream tutorials covering AUCell scoring, metacell DEG, and related exports.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bulk-rna-seq-batch-correction-with-combat Use omicverse's pyComBat wrapper to remove batch effects from merged bulk RNA-seq or microarray cohorts, export corrected matrices, and benchmark pre/post correction visualisations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-pdb-structure-io Parse and write protein structure files using Biopython Bio.PDB. Use when reading PDB, mmCIF, and MMTF files, downloading structures from RCSB PDB, or writing structures to various formats.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflows-scrnaseq-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-data-visualization-genome-browser-tracks
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tumor-heterogeneity-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
binding-characterization Guidance for SPR and BLI binding characterization experiments. Use when: (1) Planning binding kinetics experiments, (2) Troubleshooting poor/no binding signal, (3) Interpreting kinetic data artifacts, (4) Choosing between SPR vs BLI platforms.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-admet-prediction Predicts ADMET properties using ADMETlab 3.0 API or DeepChem models. Estimates bioavailability, CYP inhibition, hERG liability, and 119 toxicity endpoints with uncertainty quantification. Filters for PAINS and other structural alerts. Use when filtering compounds for drug-likeness or prioritizing leads by predicted safety.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bayesian-optimizer
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
aeon This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
alphafold-database Access AlphaFold's 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
armored-cart-design-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-causal-genomics-mendelian-randomization Estimate causal effects between exposures and outcomes using genetic variants as instrumental variables with TwoSampleMR. Implements IVW, MR-Egger, weighted median, and MR-PRESSO methods for robust causal inference from GWAS summary statistics. Use when testing whether an exposure causally affects an outcome using genetic instruments.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-causal-genomics-fine-mapping Identify likely causal variants within GWAS loci using SuSiE for sum of single effects regression and FINEMAP for shotgun stochastic search. Computes posterior inclusion probabilities and credible sets to prioritize variants for functional follow-up. Use when narrowing GWAS association signals to candidate causal variants or building credible sets for functional validation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bgpt-paper-search Search scientific papers and retrieve structured experimental data extracted from full-text studies via the BGPT MCP server. Returns 25+ fields per paper including methods, results, sample sizes, quality scores, and conclusions. Use for literature reviews, evidence synthesis, and finding experimental details not available in abstracts alone.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-alignment-msa-parsing Parse and analyze multiple sequence alignments using Biopython. Extract sequences, identify conserved regions, analyze gaps, work with annotations, and manipulate alignment data for downstream analysis. Use when parsing or manipulating multiple sequence alignments.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-bedgraph-handling
FreedomIntelligence/OpenClaw-Medical-Skills 2,009