Sponsored by

Find leads on Reddit on auto pilot

Topic: openclaw

3,425 skills in this topic.

bio-causal-genomics-mendelian-randomization Estimate causal effects between exposures and outcomes using genetic variants as instrumental variables with TwoSampleMR. Implements IVW, MR-Egger, weighted median, and MR-PRESSO methods for robust causal inference from GWAS summary statistics. Use when testing whether an exposure causally affects an outcome using genetic instruments.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
cart-design-optimizer-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-metabolomics-normalization-qc Quality control and normalization for metabolomics data. Covers QC-based correction, batch effect removal, and data transformation methods. Use when correcting technical variation in metabolomics data before statistical analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-tumor-fraction-estimation Estimates circulating tumor DNA fraction from shallow whole-genome sequencing using ichorCNA. Detects copy number alterations via HMM segmentation and calculates ctDNA percentage. Requires 0.1-1x sWGS coverage. Use when quantifying tumor burden from liquid biopsy or monitoring treatment response.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-pathway-kegg-pathways KEGG pathway and module enrichment analysis using clusterProfiler enrichKEGG and enrichMKEGG. Use when identifying metabolic and signaling pathways over-represented in a gene list. Supports 4000+ organisms via KEGG online database.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-chipseq-qc ChIP-seq quality control metrics including FRiP (Fraction of Reads in Peaks), cross-correlation analysis (NSC/RSC), library complexity, and IDR (Irreproducibility Discovery Rate) for replicate concordance. Use to assess experiment quality before downstream analysis. Use when assessing ChIP-seq data quality metrics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bulk-rna-seq-deconvolution-with-bulk2single Turn bulk RNA-seq cohorts into synthetic single-cell datasets using omicverse's Bulk2Single workflow for cell fraction estimation, beta-VAE generation, and quality control comparisons against reference scRNA-seq.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-causal-genomics-pleiotropy-detection Detect and correct for horizontal pleiotropy in Mendelian randomization analyses using MR-PRESSO for outlier removal, MR-Egger regression for directional pleiotropy, and Steiger filtering for variant directionality. Use when validating MR results, detecting pleiotropic instruments, or running sensitivity analyses for causal inference.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
gene-database Query NCBI Gene via E-utilities/Datasets API. Search by symbol/ID, retrieve gene info (RefSeqs, GO, locations, phenotypes), batch lookups, for gene annotation and functional analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-cfdna-preprocessing Preprocesses cell-free DNA sequencing data including adapter trimming, alignment optimized for short fragments, and UMI-aware duplicate removal using fgbio. Applies cfDNA-specific quality thresholds and fragment length filtering. Use when processing plasma cfDNA sequencing data before downstream analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflows-crispr-screen-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
arboreto Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
alphafold-database Access AlphaFold's 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
data-visualization-biomedical
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
biorxiv-database Efficient database search tool for bioRxiv preprint server. Use this skill when searching for life sciences preprints by keywords, authors, date ranges, or categories, retrieving paper metadata, downloading PDFs, or conducting literature reviews.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-epidemiological-genomics-transmission-inference Infer pathogen transmission networks and identify likely transmission pairs using TransPhylo and outbreak reconstruction algorithms. Estimate who-infected-whom from genomic and epidemiological data. Use when investigating outbreak transmission chains or identifying superspreaders.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-epitranscriptomics-m6a-differential
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-crispr-screens-crispresso-editing CRISPResso2 for analyzing CRISPR gene editing outcomes. Quantifies indels, HDR efficiency, and generates comprehensive editing reports. Use when analyzing amplicon sequencing data from CRISPR editing experiments to assess editing efficiency.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-compressed-files Read and write compressed sequence files (gzip, bzip2, BGZF) using Biopython. Use when working with .gz or .bz2 sequence files. Use BGZF for indexable compressed files.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-comparative-genomics-positive-selection
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-clip-seq-clip-alignment
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-clip-seq-clip-motif-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-clip-seq-clip-peak-calling
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-comparative-genomics-ancestral-reconstruction
FreedomIntelligence/OpenClaw-Medical-Skills 2,009