Topic: openclaw-skills
1,539 skills in this topic.
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glycoengineering
Analyze and engineer protein glycosylation. Scan sequences for N-glycosylation sequons (N-X-S/T), predict O-glycosylation hotspots, and access curated glycoengineering tools (NetOGlyc, GlycoShield, GlycoWorkbench). For glycoprotein engineering, therapeutic antibody optimization, and vaccine design.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-single-cell
Production-ready single-cell and expression matrix analysis using scanpy, anndata, and scipy. Performs scRNA-seq QC, normalization, PCA, UMAP, Leiden/Louvain clustering, differential expression (Wilcoxon, t-test, DESeq2), cell type annotation, per-cell-type statistical analysis, gene-expression correlation, batch correction (Harmony), trajectory inference, and cell-cell communication analysis. NEW: Analyzes ligand-receptor interactions between cell types using OmniPath (CellPhoneDB, CellChatDB), scores communication strength, identifies signaling cascades, and handles multi-subunit receptor complexes. Integrates with ToolUniverse gene annotation tools (HPA, Ensembl, MyGene, UniProt) and enrichment tools (gseapy, PANTHER, STRING). Supports h5ad, 10X, CSV/TSV count matrices, and pre-annotated datasets. Use when analyzing single-cell RNA-seq data, studying cell-cell interactions, performing cell type differential expression, computing gene-expression correlations by cell type, analyzing tumor-immune communication, or answering questions about scRNA-seq datasets.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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single-cell-preprocessing-with-omicverse
Walk through omicverse's single-cell preprocessing tutorials to QC PBMC3k data, normalise counts, detect HVGs, and run PCA/embedding pipelines on CPU, CPU–GPU mixed, or GPU stacks.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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literature-review
Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting systematic literature reviews, meta-analyses, research synthesis, or comprehensive literature searches across biomedical, scientific, and technical domains. Creates professionally formatted markdown documents and PDFs with verified citations in multiple citation styles (APA, Nature, Vancouver, etc.).
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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hemoglobinopathy-analysis-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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imaging-data-commons
Query and download public cancer imaging data from NCI Imaging Data Commons using idc-index. Use for accessing large-scale radiology (CT, MR, PET) and pathology datasets for AI training or research. No authentication required. Query by metadata, visualize in browser, check licenses.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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ligandmpnn
Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins.
For standard protein design, use proteinmpnn. For solubility optimization, use solublempnn.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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mpn-progression-monitor-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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leads-literature-mining
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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lamindb
This skill should be used when working with LaminDB, an open-source data framework for biology that makes data queryable, traceable, reproducible, and FAIR. Use when managing biological datasets (scRNA-seq, spatial, flow cytometry, etc.), tracking computational workflows, curating and validating data with biological ontologies, building data lakehouses, or ensuring data lineage and reproducibility in biological research. Covers data management, annotation, ontologies (genes, cell types, diseases, tissues), schema validation, integrations with workflow managers (Nextflow, Snakemake) and MLOps platforms (W&B, MLflow), and deployment strategies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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monarch-database
Query the Monarch Initiative knowledge graph for disease-gene-phenotype associations across species. Integrates OMIM, ORPHANET, HPO, ClinVar, and model organism databases. Use for rare disease gene discovery, phenotype-to-gene mapping, cross-species disease modeling, and HPO term lookup.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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gwas-prs
Calculate polygenic risk scores from DTC genetic data using the PGS Catalog
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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profile-report
Unified personal genomic profile report — reads a PatientProfile JSON and synthesizes all skill results into a single "Your Genomic Profile" document.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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lobster-bioinformatics
Run bioinformatics analyses using Lobster AI - single-cell RNA-seq, bulk RNA-seq, literature mining, dataset discovery, quality control, and visualization. Use when analyzing genomics data, searching for papers/datasets, or working with H5AD, CSV, GEO/SRA accessions, or biological data. Requires lobster-ai package installed.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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labstep
Interact with the Labstep electronic lab notebook API using labstepPy. Query experiments, protocols, resources, inventory, and other lab entities.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tcga-bulk-data-preprocessing-with-omicverse
Guide Claude through ingesting TCGA sample sheets, expression archives, and clinical carts into omicverse, initialising survival metadata, and exporting annotated AnnData files.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-genome-engineering-off-target-prediction
Predict CRISPR off-target sites using Cas-OFFinder and CFD scoring algorithms. Identify potential unintended cleavage sites genome-wide and assess guide specificity. Use when evaluating guide RNA specificity or selecting guides with minimal off-target risk.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-metagenomics-kraken
Taxonomic classification of metagenomic reads using Kraken2. Fast k-mer based classification against RefSeq database. Use when performing initial taxonomic classification of shotgun metagenomic reads before abundance estimation with Bracken.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-metabolomics-normalization-qc
Quality control and normalization for metabolomics data. Covers QC-based correction, batch effect removal, and data transformation methods. Use when correcting technical variation in metabolomics data before statistical analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-causal-genomics-fine-mapping
Identify likely causal variants within GWAS loci using SuSiE for sum of single effects regression and FINEMAP for shotgun stochastic search. Computes posterior inclusion probabilities and credible sets to prioritize variants for functional follow-up. Use when narrowing GWAS association signals to candidate causal variants or building credible sets for functional validation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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armored-cart-design-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-clip-seq-clip-motif-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-flow-cytometry-fcs-handling
Read and manipulate Flow Cytometry Standard (FCS) files. Covers loading data, accessing parameters, and basic data exploration. Use when loading and inspecting flow or mass cytometry data before preprocessing.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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binding-characterization
Guidance for SPR and BLI binding characterization experiments. Use when: (1) Planning binding kinetics experiments, (2) Troubleshooting poor/no binding signal, (3) Interpreting kinetic data artifacts, (4) Choosing between SPR vs BLI platforms.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009