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Topic: nanoclaw

968 skills in this topic.

bio-alignment-pairwise Perform pairwise sequence alignment using Biopython Bio.Align.PairwiseAligner. Use when comparing two sequences, finding optimal alignments, scoring similarity, and identifying local or global matches between DNA, RNA, or protein sequences.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-genome-engineering-prime-editing-design Design pegRNAs for prime editing using PrimeDesign algorithms. Generate spacer, PBS, and RT template sequences for precise genomic modifications without double-strand breaks. Use when designing prime editing experiments for precise insertions, deletions, or point mutations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
regulatory-drafter
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
wearable-analysis-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
fitness-analyzer 分析运动数据、识别运动模式、评估健身进展，并提供个性化训练建议。支持与慢性病数据的关联分析。
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-chipseq-super-enhancers Identifies super-enhancers from H3K27ac ChIP-seq data using ROSE and related tools. Use when studying cell identity genes, cancer-associated regulatory elements, or master transcription factor binding regions that cluster into large enhancer domains.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-pdb-structure-modification Modify protein structures using Biopython Bio.PDB. Use when transforming coordinates, removing atoms or residues, adding new entities, modifying B-factors and occupancies, or building structures programmatically.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
tooluniverse-chemical-compound-retrieval Retrieves chemical compound information from PubChem and ChEMBL with disambiguation, cross-referencing, and quality assessment. Creates comprehensive compound profiles with identifiers, properties, bioactivity, and drug information. Use when users need chemical data, drug information, or mention PubChem CID, ChEMBL ID, SMILES, InChI, or compound names.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-multi-omics-data-harmonization Preprocessing and harmonization of multi-omics data before integration. Covers normalization, batch correction, feature alignment, and missing value handling across data types. Use when preparing multi-omics datasets for integration analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-metabolomics-statistical-analysis Statistical analysis for metabolomics data. Covers univariate testing, multivariate methods (PCA, PLS-DA), and biomarker discovery. Use when identifying differentially abundant metabolites or building classification models.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-atac-seq-motif-deviation Analyze transcription factor motif accessibility variability using chromVAR. Use when identifying which TF motifs show variable accessibility across samples or conditions in ATAC-seq data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-pdb-structure-navigation Navigate protein structure hierarchy using Biopython Bio.PDB SMCRA model. Use when accessing models, chains, residues, and atoms, iterating over structure levels, or extracting sequences from PDB files.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-hi-c-analysis-contact-pairs Process Hi-C read pairs using pairtools. Parse alignments, filter duplicates, classify pairs, and generate contact statistics from Hi-C sequencing data. Use when processing raw Hi-C read pairs.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
clinpgx-database Access ClinPGx pharmacogenomics data (successor to PharmGKB). Query gene-drug interactions, CPIC guidelines, allele functions, for precision medicine and genotype-guided dosing decisions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
spatial-transcriptomics-tutorials-with-omicverse Guide users through omicverse's spatial transcriptomics tutorials covering preprocessing, deconvolution, and downstream modelling workflows across Visium, Visium HD, Stereo-seq, and Slide-seq datasets.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-atac-seq-nucleosome-positioning Extract nucleosome positions from ATAC-seq data using NucleoATAC, ATACseqQC, and fragment analysis. Use when analyzing chromatin organization, identifying nucleosome-free regions at promoters, or characterizing nucleosome occupancy patterns from ATAC-seq fragment size distributions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-machine-learning-biomarker-discovery
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-pathway-go-enrichment Gene Ontology over-representation analysis using clusterProfiler enrichGO. Use when identifying biological functions enriched in a gene list from differential expression or other analyses. Supports all three ontologies (BP, MF, CC), multiple ID types, and customizable statistical thresholds.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-data-visualization-upset-plots
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
interpro-database Query InterPro for protein family, domain, and functional site annotations. Integrates Pfam, PANTHER, PRINTS, SMART, SUPERFAMILY, and 11 other member databases. Use for protein function prediction, domain architecture analysis, evolutionary classification, and GO term mapping.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-single-cell-cell-annotation Automated cell type annotation using reference-based methods including CellTypist, scPred, SingleR, and Azimuth for consistent, reproducible cell labeling. Use when automatically annotating cell types using reference datasets.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
chemistry-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflow-management-wdl-workflows
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-basecalling Convert raw Nanopore signal data (FAST5/POD5) to nucleotide sequences using Dorado basecaller. Covers model selection, GPU acceleration, modified base detection, and quality filtering. Use when processing raw Nanopore data before alignment. Guppy is deprecated; use Dorado for all new analyses.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009