Topic: medical
897 skills in this topic.
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bio-single-cell-splicing
Analyzes alternative splicing at single-cell resolution using BRIE2 for probabilistic PSI estimation or leafcutter2 for cluster-based analysis with NMD detection. Identifies cell-type-specific splicing patterns. Use when analyzing isoform usage in scRNA-seq or finding splicing differences between cell populations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-image-analysis
Process and analyze tissue images from spatial transcriptomics data using Squidpy. Extract image features, segment cells/nuclei, and compute morphological features from H&E or IF images. Use when processing tissue images for spatial transcriptomics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-spatial-preprocessing
Quality control, filtering, normalization, and feature selection for spatial transcriptomics data. Calculate QC metrics, filter spots/cells, normalize counts, and identify highly variable genes. Use when filtering and normalizing spatial transcriptomics data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-spatial-transcriptomics-spatial-proteomics
Analyzes spatial proteomics data from CODEX, IMC, and MIBI platforms including cell segmentation and protein colocalization. Use when working with multiplexed imaging data, analyzing protein spatial patterns, or integrating spatial proteomics with transcriptomics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-sra-data
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-substructure-search
Searches molecular libraries for substructure matches using SMARTS patterns with RDKit. Filters compounds by pharmacophore features, functional groups, or scaffold matches with atom mapping. Use when finding compounds containing specific chemical moieties or filtering libraries by structural features.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-systems-biology-flux-balance-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-tumor-fraction-estimation
Estimates circulating tumor DNA fraction from shallow whole-genome sequencing using ichorCNA. Detects copy number alterations via HMM segmentation and calculates ctDNA percentage. Requires 0.1-1x sWGS coverage. Use when quantifying tumor burden from liquid biopsy or monitoring treatment response.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-variant-calling
Call SNPs and indels from aligned reads using bcftools mpileup and call. Use when detecting variants from BAM files or generating VCF from alignments.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-vcf-manipulation
Merge, concatenate, sort, intersect, and subset VCF files using bcftools. Use when combining variant files, comparing call sets, or restructuring VCF data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-biomarker-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-chipseq-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-crispr-screen-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-hic-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-imc-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-longread-sv-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-metabolomics-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-neoantigen-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-spatial-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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biomedical-data-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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biomedical-search
Complete biomedical information search combining PubMed, preprints, clinical trials, and FDA drug labels. Powered by Valyu semantic search.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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biomni
Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis. Use this skill when conducting multi-step biomedical research including CRISPR screening design, single-cell RNA-seq analysis, ADMET prediction, GWAS interpretation, rare disease diagnosis, or lab protocol optimization. Leverages LLM reasoning with code execution and integrated biomedical databases.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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biorxiv-database
Efficient database search tool for bioRxiv preprint server. Use this skill when searching for life sciences preprints by keywords, authors, date ranges, or categories, retrieving paper metadata, downloading PDFs, or conducting literature reviews.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bulk-rna-seq-differential-expression-with-omicverse
Guide Claude through omicverse's bulk RNA-seq DEG pipeline, from gene ID mapping and DESeq2 normalization to statistical testing, visualization, and pathway enrichment. Use when a user has bulk count matrices and needs differential expression analysis in omicverse.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009