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Topic: medical

897 skills in this topic.

bio-single-cell-batch-integration Integrate multiple scRNA-seq samples/batches using Harmony, scVI, Seurat anchors, and fastMNN. Remove technical variation while preserving biological differences. Use when integrating multiple scRNA-seq batches or datasets.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-single-cell-lineage-tracing Reconstruct cell lineage trees from CRISPR barcode tracing or mitochondrial mutations. Use when studying clonal dynamics, cell fate decisions, or developmental trajectories.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-single-cell-perturb-seq Analyze Perturb-seq and CROP-seq CRISPR screening data integrated with scRNA-seq. Use when identifying gene function through pooled genetic perturbations in single cells.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-single-cell-trajectory-inference Infer developmental trajectories and pseudotime from single-cell RNA-seq data using Monocle3, Slingshot, and scVelo for RNA velocity analysis. Use when inferring developmental trajectories or pseudotime.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-systems-biology-gene-essentiality
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-transcription-translation
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-variant-annotation Comprehensive variant annotation using bcftools annotate/csq, VEP, SnpEff, and ANNOVAR. Add database annotations, predict functional consequences, and assess clinical significance. Use when annotating variants with functional and clinical information.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-variant-calling-clinical-interpretation Clinical variant interpretation using ClinVar, ACMG guidelines, and pathogenicity predictors. Prioritize variants for diagnostic and research applications. Use when interpreting clinical significance of variants.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflow-management-cwl-workflows
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflow-management-snakemake-workflows
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflows-expression-to-pathways
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflows-riboseq-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bio-workflows-scrnaseq-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bioinformatics-singlecell
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
boltzgen All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusion (not just backbone), (4) Require precise binding geometries, (5) Using YAML-based configuration. For backbone-only generation, use rfdiffusion. For sequence-only design, use proteinmpnn. For structure validation, use boltz.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bulk-rna-seq-batch-correction-with-combat Use omicverse's pyComBat wrapper to remove batch effects from merged bulk RNA-seq or microarray cohorts, export corrected matrices, and benchmark pre/post correction visualisations.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
bulk-wgcna-analysis-with-omicverse Assist Claude in running PyWGCNA through omicverse—preprocessing expression matrices, constructing co-expression modules, visualising eigengenes, and extracting hub genes.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
cellagent-annotation
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
chai Structure prediction using Chai-1, a foundation model for molecular structure. Use this skill when: (1) Predicting protein-protein complex structures, (2) Validating designed binders, (3) Predicting protein-ligand complexes, (4) Using the Chai API for high-throughput prediction, (5) Need an alternative to AlphaFold2. For QC thresholds, use protein-qc. For AlphaFold2 prediction, use alphafold. For ESM-based analysis, use esm.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
chembl-search Search ChEMBL bioactive molecules database with natural language queries. Find compounds and assay data with Valyu semantic search.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
chemcrow-drug-discovery
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
chemical-property-lookup
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
claims-appeals
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
clinical-decision-support Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). Supports GRADE evidence grading, statistical analysis (hazard ratios, survival curves, waterfall plots), biomarker integration, and regulatory compliance. Outputs publication-ready LaTeX/PDF format optimized for drug development, clinical research, and evidence synthesis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009