Topic: codex
8,457 skills in this topic.
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hypothesis-generation
Structured hypothesis formulation from observations. Use when you have experimental observations or data and need to formulate testable hypotheses with predictions, propose mechanisms, and design experiments to test them. Follows scientific method framework. For open-ended ideation use scientific-brainstorming; for automated LLM-driven hypothesis testing on datasets use hypogenic.
x-cmd/skill 19
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gg
Search the web using Google Gemini AI, combining search results with AI-generated answers. Core Scenario: When the user needs real-time information from the web with AI-summarized responses and source citations.
x-cmd/skill 19
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tee
Redirect output to files and stdout while preserving the original command's exit code. Core Scenario: When the user needs to log command output to a file without losing the ability to check the success of the command.
x-cmd/skill 19
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stable-baselines3
Production-ready reinforcement learning algorithms (PPO, SAC, DQN, TD3, DDPG, A2C) with scikit-learn-like API. Use for standard RL experiments, quick prototyping, and well-documented algorithm implementations. Best for single-agent RL with Gymnasium environments. For high-performance parallel training, multi-agent systems, or custom vectorized environments, use pufferlib instead.
x-cmd/skill 19
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anndata
Data structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or integrating with the scverse ecosystem. This is the data format skill—for analysis workflows use scanpy; for probabilistic models use scvi-tools; for population-scale queries use cellxgene-census.
x-cmd/skill 19
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cellxgene-census
Query the CELLxGENE Census (61M+ cells) programmatically. Use when you need expression data across tissues, diseases, or cell types from the largest curated single-cell atlas. Best for population-scale queries, reference atlas comparisons. For analyzing your own data use scanpy or scvi-tools.
x-cmd/skill 19
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deeptools
NGS analysis toolkit. BAM to bigWig conversion, QC (correlation, PCA, fingerprints), heatmaps/profiles (TSS, peaks), for ChIP-seq, RNA-seq, ATAC-seq visualization.
x-cmd/skill 19
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find
Search for files and directories in a directory hierarchy with an interactive FZF application. Core Scenario: When the user needs to find files based on name, size, type, or other metadata.
x-cmd/skill 19
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pytdc
Therapeutics Data Commons. AI-ready drug discovery datasets (ADME, toxicity, DTI), benchmarks, scaffold splits, molecular oracles, for therapeutic ML and pharmacological prediction.
x-cmd/skill 19
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clinvar-database
Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs, for genomic medicine.
x-cmd/skill 19
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adaptyv
Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.
x-cmd/skill 19
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pysam
Genomic file toolkit. Read/write SAM/BAM/CRAM alignments, VCF/BCF variants, FASTA/FASTQ sequences, extract regions, calculate coverage, for NGS data processing pipelines.
x-cmd/skill 19
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perplexity-search
Perform AI-powered web searches with real-time information using Perplexity models via LiteLLM and OpenRouter. This skill should be used when conducting web searches for current information, finding recent scientific literature, getting grounded answers with source citations, or accessing information beyond the model knowledge cutoff. Provides access to multiple Perplexity models including Sonar Pro, Sonar Pro Search (advanced agentic search), and Sonar Reasoning Pro through a single OpenRouter API key.
x-cmd/skill 19
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datamol
Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery including SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.
x-cmd/skill 19
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pubchem-database
Query PubChem via PUG-REST API/PubChemPy (110M+ compounds). Search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics.
x-cmd/skill 19
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mankier
Command-line client for ManKier.com, offering manual page queries and detailed command explanation. Core Scenario: When the user needs to explain shell commands or fetch specific sections of online manual pages.
x-cmd/skill 19
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brenda-database
Access BRENDA enzyme database via SOAP API. Retrieve kinetic parameters (Km, kcat), reaction equations, organism data, and substrate-specific enzyme information for biochemical research and metabolic pathway analysis.
x-cmd/skill 19
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telegram
Send messages and files to Telegram groups or channels using bot tokens. Core Scenario: When the user needs to automate alerts or share files with Telegram chats via bot.
x-cmd/skill 19
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moonshot
Integrate Moonshot AI (Kimi) for chat and file-based context processing. Core Scenario: When the user wants to use Moonshot's large context capabilities for chat or file translation.
x-cmd/skill 19
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x-env
x-env is x-cmd's environment and package management module for installing and managing third-party software, programming language runtimes, and command-line tools. Use this skill when: installing or managing runtimes (node, python, go, bun, java, rust); installing CLI tools (jq, yq, fzf, himalaya, claude-code); managing multiple software versions (specify versions, switch versions); cleaning up unused packages; viewing installed software paths or dependencies; asking how to install software; temporarily using software in current shell session (try); permanently installing software to user environment (use); upgrading installed software versions; running scripts with specific software versions. This is the core package manager in x-cmd ecosystem.
x-cmd/skill 19
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zarr-python
Chunked N-D arrays for cloud storage. Compressed arrays, parallel I/O, S3/GCS integration, NumPy/Dask/Xarray compatible, for large-scale scientific computing pipelines.
x-cmd/skill 19
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simpy
Process-based discrete-event simulation framework in Python. Use this skill when building simulations of systems with processes, queues, resources, and time-based events such as manufacturing systems, service operations, network traffic, logistics, or any system where entities interact with shared resources over time.
x-cmd/skill 19
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latex-posters
Create professional research posters in LaTeX using beamerposter, tikzposter, or baposter. Support for conference presentations, academic posters, and scientific communication. Includes layout design, color schemes, multi-column formats, figure integration, and poster-specific best practices for visual communication.
x-cmd/skill 19
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ls
Enhanced ls command providing unified access to system resources like CPU, memory, and processes. Core Scenario: When the user needs a quick summary of files and system resource states via enhanced subcommands.
x-cmd/skill 19