Topic: clawhub
924 skills in this topic.
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bio-genome-intervals-proximity-operations
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-hi-c-analysis-matrix-operations
Balance, normalize, and transform Hi-C contact matrices using cooler and cooltools. Apply iterative correction (ICE), compute expected values, and generate observed/expected matrices. Use when normalizing or transforming Hi-C matrices.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-imaging-mass-cytometry-cell-segmentation
Cell segmentation from multiplexed tissue images. Covers deep learning (Cellpose, Mesmer) and classical approaches for nuclear and whole-cell segmentation. Use when extracting single-cell data from IMC or MIBI images after preprocessing.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-imaging-mass-cytometry-spatial-analysis
Spatial analysis of cell neighborhoods and interactions in IMC data. Covers neighbor graphs, spatial statistics, and interaction testing. Use when analyzing spatial relationships between cell types, testing for neighborhood enrichment, or identifying cell-cell interaction patterns in imaging mass cytometry data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-liquid-biopsy-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-long-read-sequencing-isoseq-analysis
Analyze PacBio Iso-Seq data for full-length isoform discovery and quantification. Use when characterizing transcript diversity or identifying novel splice variants.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-longread-medaka
Polish assemblies and call variants from Oxford Nanopore data using medaka. Uses neural networks trained on specific basecaller versions. Use when improving ONT-only assemblies or calling variants from Nanopore data without short-read polishing.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-longread-qc
Quality control for long-read sequencing data using NanoPlot, NanoStat, and chopper. Generate QC reports, filter reads by length and quality, and visualize read characteristics. Use when assessing ONT or PacBio run quality or filtering reads before assembly or alignment.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-metabolomics-msdial-preprocessing
MS-DIAL-based metabolomics preprocessing as alternative to XCMS. Covers peak detection, alignment, annotation, and export for downstream analysis. Use when processing MS-DIAL output files for R/Python analysis or when preferring GUI-based preprocessing.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-metabolomics-pathway-mapping
Map metabolites to biological pathways using KEGG, Reactome, and MetaboAnalyst. Perform pathway enrichment and topology analysis. Use when interpreting metabolomics results in the context of biochemical pathways.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-metagenomics-strain-tracking
Track bacterial strains using MASH, sourmash, fastANI, and inStrain. Compare genomes, detect contamination, and monitor strain-level variation. Use when needing sub-species resolution for outbreak tracking, transmission analysis, or within-host strain dynamics.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-methylation-based-detection
Analyzes cfDNA methylation patterns for cancer detection using cfMeDIP-seq or bisulfite sequencing with MethylDackel. Identifies cancer-specific methylation signatures and performs tissue-of-origin deconvolution. Use when using methylation biomarkers for early cancer detection or minimal residual disease.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-motif-search
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-paired-end-fastq
Handle paired-end FASTQ files (R1/R2) using Biopython. Use when working with Illumina paired reads, synchronizing pairs, interleaving/deinterleaving, or filtering paired data.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-phasing-imputation-genotype-imputation
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-population-genetics-selection-statistics
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-proteomics-differential-abundance
Statistical testing for differentially abundant proteins between conditions. Covers limma and MSstats workflows with multiple testing correction. Use when identifying proteins with significant abundance changes between experimental groups.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-proteomics-proteomics-qc
Quality control and assessment for proteomics data. Use when evaluating proteomics data quality before downstream analysis. Covers sample metrics, missing value patterns, replicate correlation, batch effects, and intensity distributions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-proteomics-quantification
Protein quantification from mass spectrometry data including label-free (LFQ, intensity-based), isobaric labeling (TMT, iTRAQ), and metabolic labeling (SILAC) approaches. Use when extracting protein abundances from MS data for differential analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-read-alignment-bwa-alignment
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-reporting-automated-qc-reports
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-restriction-enzyme-selection
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-restriction-sites
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-ribo-seq-riboseq-preprocessing
Preprocess ribosome profiling data including adapter trimming, size selection, rRNA removal, and alignment. Use when preparing Ribo-seq reads for downstream analysis of translation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009