Topic: clawhub
924 skills in this topic.
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bio-crispr-screens-base-editing-analysis
Analyzes base editing and prime editing outcomes including editing efficiency, bystander edits, and indel frequencies. Use when quantifying CRISPR base editor results, comparing ABE vs CBE efficiency, or assessing prime editing fidelity.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-codon-usage
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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spatial-communication
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-chipseq-differential-binding
Differential binding analysis using DiffBind. Compare ChIP-seq peaks between conditions with statistical rigor. Requires replicate samples. Outputs differentially bound regions with fold changes and p-values. Use when comparing ChIP-seq binding between conditions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-multi-omics-mixomics-analysis
Supervised and unsupervised multi-omics integration with mixOmics. Includes sPLS for pairwise integration and DIABLO for multi-block discriminant analysis. Use when performing supervised multi-omics integration or identifying features that discriminate between groups.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-comparative-genomics-hgt-detection
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-chipseq-motif-analysis
De novo motif discovery and known motif enrichment analysis using HOMER and MEME-ChIP. Identify transcription factor binding motifs in ChIP-seq, ATAC-seq, or other genomic peak data. Use when finding enriched DNA motifs in peak sequences.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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pdf-processing
Extract text and tables from PDF files, fill forms, merge documents. Use when working with PDF files or when the user mentions PDFs, forms, or document extraction.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-multiome-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-multi-omics-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-comparative-genomics-synteny-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-epitranscriptomics-m6a-peak-calling
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-methylation-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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clinvar-database
Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs, for genomic medicine.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-cytometry-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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solublempnn
Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation.
For standard design, use proteinmpnn. For ligand-aware design, use ligandmpnn.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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variant-interpretation-acmg
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflow-management-nextflow-pipelines
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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data-visualization-expert
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-workflows-atacseq-pipeline
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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scrna-qc
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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gget
CLI/Python toolkit for rapid bioinformatics queries. Preferred for quick BLAST searches. Access to 20+ databases: gene info (Ensembl/UniProt), AlphaFold, ARCHS4, Enrichr, OpenTargets, COSMIC, genome downloads. For advanced BLAST/batch processing, use biopython. For multi-database integration, use bioservices.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-clinical-databases-gnomad-frequencies
Query gnomAD for population allele frequencies to assess variant rarity. Use when filtering variants by population frequency for rare disease analysis or determining if a variant is common in the general population.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-expression-data-retrieval
Retrieves gene expression and omics datasets from ArrayExpress and BioStudies with gene disambiguation, experiment quality assessment, and structured reports. Creates comprehensive dataset profiles with metadata, sample information, and download links. Use when users need expression data, omics datasets, or mention ArrayExpress (E-MTAB, E-GEOD) or BioStudies (S-BSST) accessions.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009