Topic: claude-code
35,830 skills in this topic.
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bio-phylo-modern-tree-inference
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-variant-calling-clinical-interpretation
Clinical variant interpretation using ClinVar, ACMG guidelines, and pathogenicity predictors. Prioritize variants for diagnostic and research applications. Use when interpreting clinical significance of variants.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-gwas-study-explorer
Compare GWAS studies, perform meta-analyses, and assess replication across cohorts. Integrates NHGRI-EBI GWAS Catalog and Open Targets Genetics to compare study designs, effect sizes, ancestry diversity, and heterogeneity statistics. Use when comparing GWAS studies for a trait, performing meta-analysis of genetic loci, assessing replication across cohorts, or exploring the genetic architecture of complex diseases.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-read-alignment-hisat2-alignment
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-machine-learning-survival-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-rnaseq-deseq2
Production-ready RNA-seq differential expression analysis using PyDESeq2. Performs DESeq2 normalization, dispersion estimation, Wald testing, LFC shrinkage, and result filtering. Handles multi-factor designs, multiple contrasts, batch effects, and integrates with gene enrichment (gseapy) and ToolUniverse annotation tools (UniProt, Ensembl, OpenTargets). Supports CSV/TSV/H5AD input formats and any organism. Use when analyzing RNA-seq count matrices, identifying DEGs, performing differential expression with statistical rigor, or answering questions about gene expression changes.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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ctdna-dynamics-mrd-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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writing-plans
Use when you have a spec or requirements for a multi-step task, before touching code
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-single-cell-batch-integration
Integrate multiple scRNA-seq samples/batches using Harmony, scVI, Seurat anchors, and fastMNN. Remove technical variation while preserving biological differences. Use when integrating multiple scRNA-seq batches or datasets.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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chembl-search
Search ChEMBL bioactive molecules database with natural language queries. Find compounds and assay data with Valyu semantic search.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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geo-database
Access NCBI GEO for gene expression/genomics data. Search/download microarray and RNA-seq datasets (GSE, GSM, GPL), retrieve SOFT/Matrix files, for transcriptomics and expression analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-read-sequences
Read biological sequence files (FASTA, FASTQ, GenBank, EMBL, ABI, SFF) using Biopython Bio.SeqIO. Use when parsing sequence files, iterating multi-sequence files, random access to large files, or high-performance parsing.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-epitranscriptomics-m6anet-analysis
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-comparative-genomics-ortholog-inference
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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literature-review
Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting systematic literature reviews, meta-analyses, research synthesis, or comprehensive literature searches across biomedical, scientific, and technical domains. Creates professionally formatted markdown documents and PDFs with verified citations in multiple citation styles (APA, Nature, Vancouver, etc.).
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-gatk-variant-calling
Variant calling with GATK HaplotypeCaller following best practices. Covers germline SNP/indel calling, GVCF workflow for cohorts, joint genotyping, and variant quality score recalibration (VQSR). Use when calling variants with GATK HaplotypeCaller.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-fragment-analysis
Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin. Extracts nucleosome positioning patterns, fragment ratios, and DELFI-style fragmentation profiles for cancer detection. Use when leveraging fragment patterns for tumor detection or tissue-of-origin analysis.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tumor-heterogeneity-agent
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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lamindb
This skill should be used when working with LaminDB, an open-source data framework for biology that makes data queryable, traceable, reproducible, and FAIR. Use when managing biological datasets (scRNA-seq, spatial, flow cytometry, etc.), tracking computational workflows, curating and validating data with biological ontologies, building data lakehouses, or ensuring data lineage and reproducibility in biological research. Covers data management, annotation, ontologies (genes, cell types, diseases, tissues), schema validation, integrations with workflow managers (Nextflow, Snakemake) and MLOps platforms (W&B, MLflow), and deployment strategies.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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bio-systems-biology-gene-essentiality
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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nextflow-development
Run nf-core bioinformatics pipelines (rnaseq, sarek, atacseq) on sequencing data. Use when analyzing RNA-seq, WGS/WES, or ATAC-seq data—either local FASTQs or public datasets from GEO/SRA. Triggers on nf-core, Nextflow, FASTQ analysis, variant calling, gene expression, differential expression, GEO reanalysis, GSE/GSM/SRR accessions, or samplesheet creation.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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clinical-reports
Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), and patient documentation (SOAP, H&P, discharge summaries). Full support with templates, regulatory compliance (HIPAA, FDA, ICH-GCP), and validation tools.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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tooluniverse-target-research
Gather comprehensive biological target intelligence from 9 parallel research paths covering protein info, structure, interactions, pathways, expression, variants, drug interactions, and literature. Features collision-aware searches, evidence grading (T1-T4), explicit Open Targets coverage, and mandatory completeness auditing. Use when users ask about drug targets, proteins, genes, or need target validation, druggability assessment, or comprehensive target profiling.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009
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neurokit2
Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements. Applicable for heart rate variability analysis, event-related potentials, complexity measures, autonomic nervous system assessment, psychophysiology research, and multi-modal physiological signal integration.
FreedomIntelligence/OpenClaw-Medical-Skills 2,009