Topic: agentic-coding
2,023 skills in this topic.
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openai-docs
Use when the user asks how to build with OpenAI products or APIs and needs up-to-date official documentation with citations (for example: Codex, Responses API, Chat Completions, Apps SDK, Agents SDK, Realtime, model capabilities or limits); prioritize OpenAI docs MCP tools and restrict any fallback browsing to official OpenAI domains.
foryourhealth111-pixel/Vibe-Skills 1,415
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cellxgene-census
Query CZ CELLxGENE Census (61M+ cells). Filter by cell type/tissue/disease, retrieve expression data, integrate with scanpy/PyTorch, for population-scale single-cell analysis.
foryourhealth111-pixel/Vibe-Skills 1,415
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deepchem
Molecular ML with diverse featurizers and pre-built datasets. Use for property prediction (ADMET, toxicity) with traditional ML or GNNs when you want extensive featurization options and MoleculeNet benchmarks. Best for quick experiments with pre-trained models, diverse molecular representations. For graph-first PyTorch workflows use torchdrug; for benchmark datasets use pytdc.
foryourhealth111-pixel/Vibe-Skills 1,415
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data-quality-frameworks
Implement data quality validation with Great Expectations, dbt tests, and data contracts. Use when building data quality pipelines, implementing validation rules, or establishing data contracts.
foryourhealth111-pixel/Vibe-Skills 1,415
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literature-matrix
Systematic research idea discovery through paper combination matrix. Use when finding research ideas, evaluating paper combinations, building unified theoretical frameworks, or generating code skeletons from combined methods.
foryourhealth111-pixel/Vibe-Skills 1,415
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biopython
Primary Python toolkit for molecular biology. Preferred for Python-based PubMed/NCBI queries (Bio.Entrez), sequence manipulation, file parsing (FASTA, GenBank, FASTQ, PDB), advanced BLAST workflows, structures, phylogenetics. For quick BLAST, use gget. For direct REST API, use pubmed-database.
foryourhealth111-pixel/Vibe-Skills 1,415
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security-threat-model
Repository-grounded threat modeling that enumerates trust boundaries, assets, attacker capabilities, abuse paths, and mitigations, and writes a concise Markdown threat model. Trigger only when the user explicitly asks to threat model a codebase or path, enumerate threats/abuse paths, or perform AppSec threat modeling. Do not trigger for general architecture summaries, code review, or non-security design work.
foryourhealth111-pixel/Vibe-Skills 1,415
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aios-sm
Scrum Master (River). Use for user story creation from PRD, story validation and completeness checking, acceptance criteria definition, story refinement, sprint planning, backlo...
foryourhealth111-pixel/Vibe-Skills 1,415
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engineering-features-for-machine-learning
Execute create, select, and transform features to improve machine learning model performance. Handles feature scaling, encoding, and importance analysis. Use when asked to "engineer features" or "select features". Trigger with relevant phrases based on skill purpose.
foryourhealth111-pixel/Vibe-Skills 1,415
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knowledge-steward
AI工作经验知识库管理。当用户说'保存到Obsidian'、'记录这个'、'save this insight'、'memo this'、'capture this'时自动激活。将对话中的提示词、模式、问题修复、想法和效率优化保存到Obsidian知识库，并自动同步到GitHub。
foryourhealth111-pixel/Vibe-Skills 1,415
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dialectic
Minimal compatibility wrapper for vibe Dialectic Mode (multi-perspective design analysis).
foryourhealth111-pixel/Vibe-Skills 1,415
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hypogenic
Automated hypothesis generation and testing using large language models. Use this skill when generating scientific hypotheses from datasets, combining literature insights with empirical data, testing hypotheses against observational data, or conducting systematic hypothesis exploration for research discovery in domains like deception detection, AI content detection, mental health analysis, or other empirical research tasks.
foryourhealth111-pixel/Vibe-Skills 1,415
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clinical-decision-support
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). Supports GRADE evidence grading, statistical analysis (hazard ratios, survival curves, waterfall plots), biomarker integration, and regulatory compliance. Outputs publication-ready LaTeX/PDF format optimized for drug development, clinical research, and evidence synthesis.
foryourhealth111-pixel/Vibe-Skills 1,415
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ralph-loop
Codex-compatible Ralph loop runner with dual engines (compat local state loop + optional open-ralph-wiggum backend).
foryourhealth111-pixel/Vibe-Skills 1,415
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lamindb
This skill should be used when working with LaminDB, an open-source data framework for biology that makes data queryable, traceable, reproducible, and FAIR. Use when managing biological datasets (scRNA-seq, spatial, flow cytometry, etc.), tracking computational workflows, curating and validating data with biological ontologies, building data lakehouses, or ensuring data lineage and reproducibility in biological research. Covers data management, annotation, ontologies (genes, cell types, diseases, tissues), schema validation, integrations with workflow managers (Nextflow, Snakemake) and MLOps platforms (W&B, MLflow), and deployment strategies.
foryourhealth111-pixel/Vibe-Skills 1,415
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pydeseq2
Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.
foryourhealth111-pixel/Vibe-Skills 1,415
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polars
Fast in-memory DataFrame library for datasets that fit in RAM. Use when pandas is too slow but data still fits in memory. Lazy evaluation, parallel execution, Apache Arrow backend. Best for 1-100GB datasets, ETL pipelines, faster pandas replacement. For larger-than-RAM data use dask or vaex.
foryourhealth111-pixel/Vibe-Skills 1,415
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evaluating-machine-learning-models
Build this skill allows AI assistant to evaluate machine learning models using a comprehensive suite of metrics. it should be used when the user requests model performance analysis, validation, or testing. AI assistant can use this skill to assess model accuracy, p... Use when appropriate context detected. Trigger with relevant phrases based on skill purpose.
foryourhealth111-pixel/Vibe-Skills 1,415
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umap-learn
UMAP dimensionality reduction. Fast nonlinear manifold learning for 2D/3D visualization, clustering preprocessing (HDBSCAN), supervised/parametric UMAP, for high-dimensional data.
foryourhealth111-pixel/Vibe-Skills 1,415
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pysam
Genomic file toolkit. Read/write SAM/BAM/CRAM alignments, VCF/BCF variants, FASTA/FASTQ sequences, extract regions, calculate coverage, for NGS data processing pipelines.
foryourhealth111-pixel/Vibe-Skills 1,415
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datacommons-client
Work with Data Commons, a platform providing programmatic access to public statistical data from global sources. Use this skill when working with demographic data, economic indicators, health statistics, environmental data, or any public datasets available through Data Commons. Applicable for querying population statistics, GDP figures, unemployment rates, disease prevalence, geographic entity resolution, and exploring relationships between statistical entities.
foryourhealth111-pixel/Vibe-Skills 1,415
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speckit-clarify
Structured clarification workflow for underspecified requirements. Use before planning to resolve ambiguities through coverage-based questioning. Records answers in spec clarifications section.
foryourhealth111-pixel/Vibe-Skills 1,415
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pdf
Use when tasks involve reading, creating, or reviewing PDF files where rendering and layout matter; prefer visual checks by rendering pages (Poppler) and use Python tools such as `reportlab`, `pdfplumber`, and `pypdf` for generation and extraction.
foryourhealth111-pixel/Vibe-Skills 1,415
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imaging-data-commons
Query and download public cancer imaging data from NCI Imaging Data Commons using idc-index. Use for accessing large-scale radiology (CT, MR, PET) and pathology datasets for AI training or research. No authentication required. Query by metadata, visualize in browser, check licenses.
foryourhealth111-pixel/Vibe-Skills 1,415