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Agent skills
claude-code

Topic: claude-code

35,830 skills in this topic.

vercel-react-best-practices React and Next.js performance optimization guidelines from Vercel Engineering. This skill should be used when writing, reviewing, or refactoring React/Next.js code to ensure optimal performance patterns. Triggers on tasks involving React components, Next.js pages, data fetching, bundle optimization, or performance improvements.
shep-ai/shep 126
contextual-commit Write contextual commits that capture intent, decisions, and constraints alongside code changes. Use when committing code, finishing a task, or when the user asks to commit. Extends Conventional Commits with structured action lines in the commit body that preserve WHY code was written, not just WHAT changed.
berserkdisruptors/contextual-commits 125
recall Reconstruct and narrate the current development context from contextual commits. Run at session start, when resuming work, or when switching branches. Produces a brief, conversational summary of where things stand.
berserkdisruptors/contextual-commits 125
debugging Debug and troubleshoot issues
saadnvd1/agent-os 127
db-migrate Миграция схемы базы данных: SQLite → PostgreSQL/Supabase. Генерация SQL, проверка совместимости.
alexeykrol/claude-code-starter 125
finish Завершение рабочей сессии. Тесты, коммит, обновление SNAPSHOT, отчёт.
alexeykrol/claude-code-starter 125
housekeeping Фоновое обслуживание проекта: актуальность README, CHANGELOG, версии, .gitignore, метафайлов.
alexeykrol/claude-code-starter 125
playwright E2E тестирование UI с Playwright. Запуск, создание тестов, анализ результатов.
alexeykrol/claude-code-starter 125
start Инициализация рабочей сессии. Загрузить состояние проекта, оценить готовность, доложить.
alexeykrol/claude-code-starter 125
testing Запуск тестов проекта: unit, integration. Определение типа проекта и выбор стратегии.
alexeykrol/claude-code-starter 125
alphafold Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm. For QC thresholds, use protein-qc.
adaptyvbio/protein-design-skills 125
bindcraft End-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using different design protocols (fast, default, slow), (4) Need joint backbone and sequence optimization, (5) Want high experimental success rate. For backbone-only generation, use rfdiffusion. For QC thresholds, use protein-qc. For tool selection guidance, use binder-design.
adaptyvbio/protein-design-skills 125
binder-design Guidance for choosing the right protein binder design tool. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types. For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).
adaptyvbio/protein-design-skills 125
binding-characterization Guidance for SPR and BLI binding characterization experiments. Use when: (1) Planning binding kinetics experiments, (2) Troubleshooting poor/no binding signal, (3) Interpreting kinetic data artifacts, (4) Choosing between SPR vs BLI platforms.
adaptyvbio/protein-design-skills 125
boltz Structure prediction using Boltz-1/Boltz-2, an open biomolecular structure predictor. Use this skill when: (1) Predicting protein complex structures, (2) Validating designed binders, (3) Need open-source alternative to AF2, (4) Predicting protein-ligand complexes, (5) Using local GPU resources. For QC thresholds, use protein-qc. For AlphaFold2 prediction, use alphafold. For Chai prediction, use chai.
adaptyvbio/protein-design-skills 125
boltzgen All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusion (not just backbone), (4) Require precise binding geometries, (5) Using YAML-based configuration. For backbone-only generation, use rfdiffusion. For sequence-only design, use proteinmpnn. For structure validation, use boltz.
adaptyvbio/protein-design-skills 125
campaign-manager Goal-oriented binder design campaign planning and health assessment. Use this skill when: (1) Planning a complete binder design campaign, (2) Converting high-level goals into runnable pipelines, (3) Assessing campaign health and pass rates, (4) Diagnosing why designs are failing QC, (5) Estimating time, cost, and expected yields, (6) Selecting between design tools for a specific target. This skill orchestrates the other protein design tools. For individual tool parameters, use the specific tool skills.
adaptyvbio/protein-design-skills 125
cell-free-expression Guidance for cell-free protein synthesis (CFPS) optimization. Use when: (1) Planning CFPS experiments, (2) Troubleshooting low yield or aggregation, (3) Optimizing DNA template design for CFPS, (4) Expressing difficult proteins (disulfide-rich, toxic, membrane).
adaptyvbio/protein-design-skills 125
chai Structure prediction using Chai-1, a foundation model for molecular structure. Use this skill when: (1) Predicting protein-protein complex structures, (2) Validating designed binders, (3) Predicting protein-ligand complexes, (4) Using the Chai API for high-throughput prediction, (5) Need an alternative to AlphaFold2. For QC thresholds, use protein-qc. For AlphaFold2 prediction, use alphafold. For ESM-based analysis, use esm.
adaptyvbio/protein-design-skills 125
esm ESM2 protein language model for embeddings and sequence scoring. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) scores, (2) Getting protein embeddings for clustering, (3) Filtering designs by sequence plausibility, (4) Zero-shot variant effect prediction, (5) Analyzing sequence-function relationships. For structure prediction, use chai or boltz. For QC thresholds, use protein-qc.
adaptyvbio/protein-design-skills 125
foldseek Structure similarity search with Foldseek. Use this skill when: (1) Finding similar structures in PDB/AFDB databases, (2) Structural homology search, (3) Database queries by 3D structure, (4) Finding remote homologs not detected by sequence, (5) Clustering structures by similarity. For sequence similarity, use uniprot BLAST. For structure prediction, use chai or boltz.
adaptyvbio/protein-design-skills 125
ipsae Binder design ranking using ipSAE (interprotein Score from Aligned Errors). Use this skill when: (1) Ranking binder designs for experimental testing, (2) Filtering BindCraft or RFdiffusion outputs, (3) Comparing AF2/AF3/Boltz predictions, (4) Predicting binding success rates, (5) Need better ranking than ipTM or iPAE. For structure prediction, use chai or alphafold. For QC thresholds, use protein-qc.
adaptyvbio/protein-design-skills 125
ligandmpnn Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use proteinmpnn. For solubility optimization, use solublempnn.
adaptyvbio/protein-design-skills 125
pdb Fetch and analyze protein structures from RCSB PDB. Use this skill when: (1) Need to download a structure by PDB ID, (2) Search for similar structures, (3) Prepare target for binder design, (4) Extract specific chains or domains, (5) Get structure metadata. For sequence lookup, use uniprot. For binder design workflow, use binder-design.
adaptyvbio/protein-design-skills 125