ReddRadar
Agent skill
pharmgkb-annotator
PharmGKB pharmacogenomics annotation skill for drug-gene interaction assessment
Install this agent skill to your Project
npx add-skill https://github.com/a5c-ai/babysitter/tree/main/library/specializations/domains/science/bioinformatics/skills/pharmgkb-annotator
Metadata
Additional technical details for this skill
- tags
-
clinical-genomics pharmacogenomics drug-response cpic
- version
- 1.0
- category
- bioinformatics
SKILL.md
PharmGKB Annotator Skill
Purpose
Provide PharmGKB pharmacogenomics annotation for drug-gene interaction assessment.
Capabilities
- Star allele calling (Stargazer)
- Diplotype determination
- CPIC guideline integration
- Drug recommendation generation
- Clinical annotation lookup
- Dosing guidance extraction
Usage Guidelines
- Call star alleles accurately
- Determine diplotypes from genotypes
- Apply CPIC guidelines for dosing
- Generate actionable recommendations
- Review clinical annotations
- Document guideline versions
Dependencies
- PharmGKB API
- Stargazer
- PharmCAT
Process Integration
- Pharmacogenomics Analysis (pharmacogenomics-analysis)
- Clinical Variant Interpretation (clinical-variant-interpretation)
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